Vaccines

Giving Flu Shots in Pharmacies Could Up Vaccination Coverage

October 18, 2018

The researchers found that adding pharmacies with typical business hours averted 11.9 million symptomatic influenza cases, 23,577 to 94,307 deaths, $1.0 billion in direct costs, and $4.2 to 44.4 billion in productivity losses,

Number of Children Not Receiving Vaccines Slightly Increased

October 16, 2018

Although remaining low, the proportion of children who received no vaccine doses by age 24 months increased gradually from 0.9% for children born in 2011 to 1.3% for children born in 2015.

Flu Vaccine Cuts Hospitalization Rates in Pregnant Women

October 15, 2018

Influenza vaccine effectiveness was examined for several countries against laboratory-confirmed influenza-associated hospitalizations during pregnancy.

Gardasil 9 Approved for Use in Women and Men 27 Through 45 Years Old

By October 09, 2018

The approval of the expanded age range was based on data from a clinical trial which evaluated the efficacy of Gardasil (quadrivalent human papillomavirus recombinant vaccine) in 3253 women 27-45 years of age with a median duration of follow-up of 3.5 years post-dose 3.

FDA Approves Accelerated Vaccination Schedule for Ixiaro

By October 05, 2018

Previously, the prescribing information stated that adults should receive the 2 doses 28 days apart.

Multivalent Pneumococcal Conjugate Vaccine Gets Breakthrough Tx Designation

By September 20, 2018

The Breakthrough designation follows an FDA examination of results from a Phase 2 randomized, double-blind trial which evaluated the safety and immunogenicity of the treatment in adults aged 60 to 64 years.

Active Choice Intervention Tied to Increase in Flu Shot Rates

September 19, 2018

Compared with control practices over time, the active choice intervention correlated with a significant 9.5% increase in vaccination rates, in adjusted analyses. Similar increases were seen in vaccination rates across times of the day.

AAP Issues Updated Influenza Vaccine Recommendations

By September 06, 2018

According to the Centers for Disease Control and Prevention (CDC), the 2017-2018 flu season was one of the most severe - excluding pandemics - on record.

CDC: HPV Vaccination Rates Increasing Among Adolescents

September 05, 2018

The researchers found that coverage increased for 1 or more dose of HPV vaccine (60.4 to 65.5%), 1 or more dose of meningococcal conjugate vaccine (MenACWY; 82.2 to 85.1%), and 2 or more doses of MenACWY (39.1 to 44.3%) from 2016 to 2017.

Knowledge of Herd Immunity Can Up Willingness to Be Vaccinated

August 24, 2018

"Education about herd immunity and local vaccination coverage could be a useful tool for increasing willingness to vaccinate, generating benefits both to individuals and communities," the authors write.

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

By August 23, 2018

In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.

Catch-Up HPV Doses Effective to Age 21 Against Cervical Neoplasia

August 22, 2018

The strongest protection against CIN2+ was among women who had received at least 3 vaccine doses and had received their first dose at age 14 to 17 years (RR, 0.52) or age 18 to 20 years (RR, 0.65). In women 21 years or older at the time of first dose.

Does Adolescent Vaccination Increase Primary Ovarian Insufficiency Risk?

By August 21, 2018

For this study, researchers investigated the incidence of primary ovarian insufficiency incidence and estimated risk for POI after vaccination with human papillomavirus, Tdap, influenza and meningococcal conjugate using Kaiser Permanente Northwest electronic health records from 2006 to 2014.

Does HPV Legislation Impact Teen Sexual Behaviors?

August 16, 2018

No substantive or significant associations between HPV legislation and adolescent sexual behaviors

Does Prenatal Tdap Vaccination Increase Autism Risk in Offspring?

By August 14, 2018

Currently, the Advisory Committee on Immunization Practices (ACIP) recommends pregnant women receive the Tdap vaccination to prevent pertussis infection.

Flu Vaccine Cuts Mortality in Rheumatoid Arthritis Patients

August 01, 2018

The researchers, after adjusting for potential confounding factors, found that RA patients who received the influenza vaccine had reduced risk of hospitalization for septicemia, bacteremia, or viremia.

No Higher Risk of Autoimmune Disorders After HPV4 Vaccination

July 30, 2018

No significant risks were seen in exploratory analyses of individual autoimmune disorders, including Bell's palsy, optic neuritis, and Graves' disease.

HPV Vaccine Eliminates Advanced Skin Cancer in 97-Year-Old

July 24, 2018

Doctors tried an unorthodox approach - injecting each tumor with Gardasil, the HPV vaccine. The result: All the tumors completely and rapidly disappeared.

Quadrivalent HPV Vaccine Not Tied to Spontaneous Abortion

July 17, 2018

No evidence of increased risk of spontaneous abortion when inadvertently given before or during pregnancy

Novel Mosaic HIV Vaccine Safe, Immunogenic in Healthy Adults and Monkeys

By July 13, 2018

The regimens were well-tolerated as evident by the comparable incidence of local and systemic reactions among all treatment arms. No grade 4 adverse events or death were reported.

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

July 12, 2018

The researchers estimated that in HIV-uninfected children aged 1 to 59 months in 2015 there were 294,000 pneumococcal deaths and 29,500 Hib deaths.

Public Health Vaccine Opposition Growing in the United States

July 10, 2018

The authors note that in recent years, a social movement of public health vaccine opposition has been growing in the United States, with an increase in measles outbreaks.

Mammography Use Tied to Other Preventive Tests in Older Women

July 09, 2018

The researchers found that women who underwent index screening mammography were more likely than unscreened women to later undergo Papanicolaou test (odds ratio, 1.49), bone mass measurement (odds ratio, 1.70), and influenza vaccine (odds ratio, 1.45).

Immunogenicity of Co-Administered Herpes Zoster, Pneumonia Vaccine Assessed

By July 06, 2018

In this Phase 3, open-label, randomized, controlled multicenter study, a total of 865 patients were randomized to receive one of the following vaccine regimens: (1) the first RZV dose and PPSV23 together on Day 0 and the second dose of RZV at Month 2 (N=432); or (2) PPSV23 on Day 0 and then first RZV dose at Month 2 with the second RZV dose at Month 4 (N=433; control group).

Hepatitis B Vaccines Compared in Older Adults With Type 2 Diabetes

By June 26, 2018

For the analysis, study authors looked at data specifically for patients with type 2 diabetes aged 60 to 70 years.

Immunogenicity of Hepatitis A Vaccine Investigated in Older Patients

By June 25, 2018

"All found higher proportions seroprotected (definition varied by study) in younger age groups (ages varied by study) at 15 days post-vaccination but similar seroprotection at 30 days," the study authors reported.

BCG Vaccine Tied to Reduced Hyperglycemia in Type 1 Diabetes

June 22, 2018

Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis

Parents Say Cancer Prevention Best Reason for HPV Vaccination

June 21, 2018

Findings based on large survey of parents to assess best, worst reasons for vaccination

Varicella Vaccination and Pediatric Arterial Ischemic Stroke: Is There a Link?

By June 20, 2018

The study authors reported that the rate of AIS in the 12 months following vaccination was 7.8 per 100,000 person-years at risk (95% CI: 4.8, 10.9) in patients who received the vaccine versus 6.8 (95% CI: 1.3, 12.2) in those who did not.

HPV Vaccine Under Priority Review for Expanded Age Range

By June 13, 2018

Specifically, the types the vaccine protects against are HPV 16, 18, 31, 33, 45, 52, 58 (which cause ~90% of cervical cancer cases worldwide), and types 6 and 11 which case genital warts.