Urological Disorders

Dapagliflozin Evaluated in Patients With T2D and Moderate Renal Impairment

By March 20, 2018

Farxiga is a sodium-glucose co-transporter 2 (SGLT2) inhibitor currently indicated as an adjunct to diet and exercise to improve glycemic control in adults with T2D mellitus.

Low Sperm Count Associated With Worse Cardiometabolic Health

March 19, 2018

Low sperm counts linked to hypogonadism, higher BMI, hypertension, dyslipidemia, metabolic syndrome

FDA Warns Against Unapproved Meds Advertised on Radio Stations

By March 19, 2018

The manufacturers on the blister packs of these drugs show Acme Generics and Sun Pharma. The FDA also expressed concern that the seller may be distributing unapproved tadalafil, the generic version of Cialis

CDC: Acute Kidney Injury Hospitalization Rates Examined in the U.S.

By March 16, 2018

For the report, AKI was defined as the occurrence of at least 1 diagnostic code 584 (acute renal failure) or the occurrence of at least 1 procedure code of 39.95 (hemodialysis) or 54.98 (peritoneal dialysis).

Balanced crystalloids decreases adverse kidney events compared to saline among critically ill

March 06, 2018

Use of balanced crystalloids (lactated Ringers or Plasma-Lyte A) was associated with a significant reduction in acute kidney injury events compared to normal saline among intensive care unit (ICU) patients.

Combination Antibiotics Compared in the Treatment of Complicated UTI

By February 28, 2018

The results showed that meropenem/vaborbactam was non-inferior to piperacillin/tazobactam with an overall success rate of 98.4% vs 94.0%.

Balanced Crystalloids May Cut Kidney Complications Compared With Saline

By February 28, 2018

The results showed no difference in the number of hospital-free days between either group but the balanced crystalloids group had a lower incidence of major adverse kidney events ≤30 days vs the saline group.

Cognitive Impact of Chronic Kidney Disease in Children, Investigated

February 23, 2018

The mean differences in FSIQ were −10.5 for all CKD stages, −9.39 predialysis, −16.2 for dialysis, and −11.2 for transplant compared with the general population.

Ulipristal Assessed in Symptomatic Uterine Leiomyomas

February 20, 2018

The researchers found that amenorrhea was achieved by 47.2, 58.3, and 1.8% of patients in the ulipristal 5mg and 10mg, and placebo groups, respectively.

No benefit of sodium bicarbonate or acetylcysteine for prevention of complications after angiography

February 15, 2018

Amongst patients undergoing angiography, neither sodium bicarbonate nor acetylcysteine were effective in preventing a composite outcome of death, need for dialysis, or persistent kidney injury.

Addressing Sensitive Topics With Patients: An Interview With Windel Stracener, MD

By February 14, 2018

"Patients must feel that you are empathetic and do not judge them. This is key not only to discussing weight, but to any subject that comes up," said Dr Windel Stracener, a family practitioner for 22 years.

Statin Use May Protect Against Kidney Stone Formation

By February 09, 2018

For this study, researchers aimed to determine the impact of statin use on the risk of nephrolithiasis and to assess whether higher lipid levels were associated with the risk of stone formation.

Nymox Plans to Submit NDA for Novel Benign Prostatic Hyperplasia Treatment

By February 07, 2018

Fexapotide triflutate 2.5 mg was found to be safe and effective for long-term treatment of BPH.

Transgender, gender nonconforming youths underutilize health care

February 05, 2018

Nearly twice the number of youths who identify as transgender or gender nonconforming (TGNC) stated their health to be fair, poor, or good as opposed to very good or excellent when compared with youths who identified as cisgender.

Toxic Plant Extract Shows Promise in Early Male Birth Control Studies

February 02, 2018

While the male hormonal birth control pill option is in clinical human trials and likely closer to market, it has several potential side effects: In addition to potentially causing weight gain and changes in libido.

Living kidney donation associated with some increased health risks

January 31, 2018

Living kidney donation was associated with higher diastolic blood pressure, lower estimated glomerular filtration rates, and increased relative risk of preeclampsia and end-stage renal disease (ESRD).

Do Statins, BP-Lowering Meds Impact Erectile Function?

January 31, 2018

No significant effect for rosuvastatin, CandHCTZ, or both versus placebo in men aged 55 years

FDA Approves Generic Bumex Tablets

By January 30, 2018

The company stated that they are prepared to begin shipping product to wholesalers in early February 2018.

Confusion Common in Seniors Prescribed Antibiotics for UTI

January 22, 2018

One in 5 NH residents had received antibiotics within the last 30 days, of which 45% were for UTI.

Sensitivity, Specificity of Urinalysis for UTIs Assessed in Febrile Infants

January 22, 2018

In all groups, specificity was 0.91 (95% CI, 0.90 to 0.91). The sensitivity and specificity of urinalysis was 0.87 (95% CI, 0.83 to 0.90) and 0.91 (95% CI, 0.90 to 0.92), respectively, for UTIs with colony counts ≥10,000 CFUs/mL.

Nitrofurantoin, TMP-SMX Often Prescribed in Early Pregnancy for UTI

By January 17, 2018

A 2011 committee opinion from the American College of Obstetricians and Gynecologists (ACOG) recommended that sulfonamides and nitrofurantoin may be prescribed in the first trimester of pregnancy only when other antimicrobial therapies are deemed clinically inappropriate.

Urinalysis highly sensitive and specific for UTI in febrile infants

January 16, 2018

Urinalysis had ≥90% sensitivity and specificity in identifying urinary tract infection (UTI) among infants ≤60 days old with fever, regardless of presence of associated bacteremia.

FDA Clears UriVarx Test Strips for UTI Detection

By January 11, 2018

The supplements are intended to reduce urinary urgency, accidents, and day/night frequency in patients with overactive bladder and urinary infections.

Kidney Injury Incidence Following Non-Kidney Transplants Common in Children

January 09, 2018

The researchers assessed AKI in the first year after transplant and found that perioperative AKI (within the first week) occurred in 67% of children and that AKI after the first week occurred in 36%.

Regional variation in CT imaging is associated with nephrectomy risk

January 03, 2018

Regional variation in cumulative risk of an individual having a chest or abdominal CT in the United States was positively correlated with the risk of both total and partial nephrectomy, as well as any renal procedure (including renal ablation).

Outcomes after left ventricular assist device implantation significantly worse for those with end-stage renal disease

January 03, 2018

Patients with end-stage renal disease (ESRD) have significantly worse survival outcomes following left ventricular assist device (LVAD) implantation compared to recipients without ESRD.

Benign Prostatic Hyperplasia Treatments

December 26, 2017

Benign prostatic hyperplasia (BPH) treatment chart including drug dosing, formulation, strength, and pharmacological class.

Emergency-Only Hemodialysis Tied to Higher-Mortality Rates

December 19, 2017

The mean 3-year relative hazard of mortality was increased for patients receiving emergency-only versus standard hemodialysis after adjustment for propensity score (hazard ratio, 4.96; 95% confidence interval, 0.93 to 26.45; P=0.06).

Hospital Admissions for <i>C. difficile</i> Infection and Acute Kidney Injury Increasing

December 13, 2017

Despite increase in admissions, inpatient mortality improved from 2003 to 2012

Teva Announces Availability of Generic Viagra

By December 11, 2017

Sildenafil tablets are a phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction.