Acetohydroxamic acid, which has proven a successful antibiotic treatment of urea-splitting Proteus infections after surgical removal of struvite stones, was in shortage since July 2014.
An association between albuminuria and cognitive decline may be mediated by shared microvascular pathology in the kidney and the brain.
Hydroxycitrate, a natural fruit extract available as a dietary supplement, may dissolve a key component of kidney stones, potentially offering a new prevention tool against the condition, according to a study published online August 8 in Nature.ment that has side effects
Delaying surgery for nephrolithiasis can increase the risk of complications, raising health care costs, a new study finds.
Greater dietary intake of fiber, fruits, and vegetables is associated with a reduced risk of incident kidney stones in postmenopausal women.
The risk of diabetes mellitus is not increased with thiazide diuretic prophylaxis for kidney stones, according to new research.
AstraZeneca announced top-line results for two pivotal Phase 3 trials investigating lesinurad, when used in combination with xanthine oxidare (XO) inhibitor allopurinol in patients with symptomatic gout not achieving target sUA levels on current allopurinol dose.
Increased fluid intake is recommended to prevent recurrent nephrolithiasis, with pharmacological monotherapy suggested for patients in whom increased fluid intake fails to reduce stone formation.
No significant difference in outcomes is observed between the use of ultrasonography or computed tomography (CT) for suspected nephrolithiasis.
The Recurrence of Kidney Stone (ROKS) nomogram identifies patients with kidney stones who are at high risk for a second symptomatic episode.
Guideline statements have been developed for the diagnosis, prevention, and follow-up of patients with kidney stones, and published in the August issue of The Journal of Urology.
For patients undergoing procedures to fragment or remove urinary stones, one in seven require an unplanned post-procedural visit, and these visits are associated with considerable expenditure.
The FDA issued a Complete Response Letter in response to an NDA filing for tolvaptan (Otsuka) for the treatment of adult patients with rapidly progressing autosomal dominant polycystic kidney disease (ADPKD).
A high urinary albumin-to-creatinine ratio at baseline is associated with a higher risk of a first coronary heart disease (CHD) event in blacks compared with whites.
The FDA has granted Soliris (eculizumab) Orphan Drug Designation for the treatment of neuromyelitis optica, a rare neurological disorder.