Urinary Tract Discomfort

UTI Calculator Predicts Risk of Infant Urinary Tract Infection

April 17, 2018

The researchers analyzed electronic medical records from a training database of 1,686 febrile children (aged 2 to 23 months) presenting to the emergency department.

Inactivity, Prolonged Sitting Tied to Urinary Tract Infections in Men

March 27, 2018

The researchers found that the incidence rate of significant LUTS was 39 per 1,000 person-years. Both low physical activity level and prolonged sitting time were independently associated with the incidence of LUTS after adjustment for multiple factors.

Combination Antibiotics Compared in the Treatment of Complicated UTI

By February 28, 2018

The results showed that meropenem/vaborbactam was non-inferior to piperacillin/tazobactam with an overall success rate of 98.4% vs 94.0%.

Confusion Common in Seniors Prescribed Antibiotics for UTI

January 22, 2018

One in 5 NH residents had received antibiotics within the last 30 days, of which 45% were for UTI.

Sensitivity, Specificity of Urinalysis for UTIs Assessed in Febrile Infants

January 22, 2018

In all groups, specificity was 0.91 (95% CI, 0.90 to 0.91). The sensitivity and specificity of urinalysis was 0.87 (95% CI, 0.83 to 0.90) and 0.91 (95% CI, 0.90 to 0.92), respectively, for UTIs with colony counts ≥10,000 CFUs/mL.

Nitrofurantoin, TMP-SMX Often Prescribed in Early Pregnancy for UTI

By January 17, 2018

A 2011 committee opinion from the American College of Obstetricians and Gynecologists (ACOG) recommended that sulfonamides and nitrofurantoin may be prescribed in the first trimester of pregnancy only when other antimicrobial therapies are deemed clinically inappropriate.

FDA Clears UriVarx Test Strips for UTI Detection

By January 11, 2018

The supplements are intended to reduce urinary urgency, accidents, and day/night frequency in patients with overactive bladder and urinary infections.

NSAID Compared to Antibiotic for Symptomatic Treatment of UTI

By November 09, 2017

The primary endpoint of symptom resolution at day 3 was met by 54% (72/133) in the diclofenac group vs. 80% (96/120) in the norfloxacin group (risk difference 27%, 95% CI 15% to 38%, P=0.98 for non-inferiority, P<0.001 for superiority).

FDA Approves Unique Antibiotic Combo Drug Vabomere

By August 30, 2017

Vabomere is a combination antibiotic that includes meropenem, a penem antibacterial, and vaborbactam, a non-suicidal beta-lactamase inhibitor.

Cephalosporin Antibiotic Formulation Discontinued

By July 24, 2017

Specifically, the following presentations will no longer be available: 125mg/5mL; 100mL bottles (anticipated final date of availability: April 1, 2018), 250mg/5mL; 50mL bottles (anticipated final date of availability: January 15, 2018), 250mg/5mL; 100mL bottles (anticipated final date of availability: February 15, 2018)

"UTI" Diagnosis May Lead to Harmful Antibiotic Overtreatment

By June 05, 2017

In their paper, the authors noted that "healthy urinary tracts host a ubiquitous, complex microbial community" and that the presence of these microorganisms are often beneficial to overall well-being.

AUA 'Choosing Wisely' List IDs Unnecessary Tests, Treatments

By May 15, 2017

The 2017 AUA list contains evidence-based recommendations to guide conversations between physicians and patients about what care is appropriate.

Positive Results for Plazomicin for cUTI, CRE Infections

By December 12, 2016

Achaogen has announced positive results from the Phase 3 trials ('EPIC' and 'CARE') of plazomicin, a lead candidate for potential treatment of complicated urinary tract infections (cUTI) and acute pyelonephritis (AP).

Guidelines for UTI in Febrile Infants and Young Children Reaffirmed

November 29, 2016

2011 CPG on urinary tract infection in infants and young children reaffirmed after review of literature

UTI Treatment Leads to Fatal Drug Interaction in a Schizophrenia Patient

By November 23, 2016

This case is the first to describe a fatal outcome with such an interaction.

Year Long Study Examines Efficacy of Cranberry Capsules in Preventing UTIs

October 28, 2016

There is no significant difference in the presence of bacteriuria plus pyuria over one year among older women living in nursing homes receiving cranberry capsules versus a placebo pill, according to a study published online October 27 in the Journal of the American Medical Association. The research was published to coincide with the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 26 to 30 in New Orleans.

Treatment of UTI Leads to Fatal Hepatotoxicity

By October 19, 2016

This antibiotic class is rarely linked to liver injury.

Study IDs Urinalysis Marker for UTI Diagnosis in Young Adults

October 19, 2016

For infants undergoing microscopic urinalysis as part of urinary tract infection (UTI) evaluation, urine concentration should be included in the interpretation, according to a study published online in Pediatrics.

FDA to Review New Data for Avycaz in Complicated UTI

By October 14, 2016

The Food and Drug Administration (FDA) has accepted a supplemental New Drug Application (sNDA) for Avycaz (ceftazidime and avibactam; Allergen), for the addition of new Phase 3 data to the label.

Reasons for Inappropriate Antibiotic Prescribing Explored in Elderly

September 29, 2016

Constitutional symptoms, including mentation, often lead to diagnostic testing and potentially inappropriate antibiotic prescribing in older patients suspected of having a urinary tract infection (UTI) or pneumonia, according to a study published online in the Journal of the American Geriatrics Society.

Bacteriuria ID'd as Possible Trigger of Higher Edema Incidence

August 25, 2016

For patients with hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE), those with bacteriuria have a higher number of edematous attacks, according to a study published online in Allergy.

High Specificity, Low Sensitivity in Onsite Tests for Asymptomatic Bacteriuria

August 15, 2016

Onsite tests have high specificity for detecting asymptomatic bacteriuria among pregnant women, but sensitivity is lower, according to a review published in the September issue of Obstetrics & Gynecology.

Over Half of Pediatric Patients with UTI Resistant to Antibiotic, Study Finds

March 17, 2016

Many children who develop urinary tract infections (UTIs) tied to the Escherichia coli bacteria are now failing to respond to antibiotic treatment, according to research published online March 15 in The BMJ.

Stone Removal May Not Help All Patients for Recurrent UTI

September 28, 2015

Half of patients with recurrent urinary tract infections and asymptomatic renal calculi can be rendered infection-free with stone extraction, according to a study published in The Journal of Urology.

Cranberry Juice Capsules May Cut UTI Risk After Gynecological Surgery

July 30, 2015

Cranberry juice capsules may reduce the rate of urinary tract infection (UTI) in women undergoing elective benign gynecological surgery involving urinary catheterization.

Nocturia, Reassurance Key Drivers for Men Seeking LUTS Care

July 01, 2015

Overall, men with LUTS showed remarkably poor knowledge about their symptoms

Brain Abnormalities Linked to Interstitial Cystitis/Bladder Pain Syndrome

June 19, 2015

Brain abnormalities linked to symptoms of interstitial cystitis/bladder pain syndrome

AUA Discusses Antimicrobials, PSA Testing in New <i>Choosing Wisely</i> Recommendations

By June 12, 2015

The American Urological Association (AUA) has issued a new list of recommendations as part of the Choosing Wisely campaign.

Common Rx for UTIs in Older Women May Not Be Best Choice

May 01, 2015

Nitrofurantoin may not be the most effective option for treatment of urinary tract infections in older women, according to a new new study.

Cranberries May Be as Effective in UTI Prevention as Antibiotics, Study Finds

By April 28, 2015

Cranberry extract may lower the risk of urinary tract infection (UTI) by 50% in women who have a catheter in place while undergoing elective gynecological surgery.