TRULANCE Rx

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TRULANCE

Colorectal disorders
Constipation and bowel cleansers
Only 4 drugs may be compared at once

Generic Name and Formulations:

Plecanatide 3mg; tabs.

Select therapeutic use:

Indications for TRULANCE:

Irritable bowel syndrome with constipation (IBS-C).

Adult:

Take with or without food. Swallow whole; if difficulties in swallowing, may crush tabs and mix in applesauce or water; may also give with water via NG or gastric feeding tube. ≥18yrs: 3mg once daily.

Children:

<18yrs: not established.

Contraindications:

Children <6yrs of age. Known or suspected mechanical GI obstruction.

Boxed Warning:

Risk of serious dehydration in pediatric patients.

Warnings/Precautions:

Avoid use in patients 6–<18yrs of age. Suspend dosing and rehydrate if severe diarrhea occurs. Pregnancy. Nursing mothers.

Pharmacological Class:

Guanylate cyclase-C agonist.

Adverse Reactions:

Diarrhea (may be severe), sinusitis, URTI, abdominal distension/tenderness, flatulence, increased liver enzymes, nausea, nasopharyngitis, UTI, dizziness.

Generic Availability:

NO

How Supplied:

Tabs—30

TRULANCE 30 tablets of 3mg dose packs (Qty:1)

appx. price $406.00

Indications for TRULANCE:

Chronic idiopathic constipation (CIC).

Adult:

Take with or without food. Swallow whole; if difficulties in swallowing, may crush tabs and mix in applesauce or water; may also give with water via NG or gastric feeding tube. ≥18yrs: 3mg once daily.

Children:

<18yrs: not established.

Contraindications:

Children <6yrs of age. Known or suspected mechanical GI obstruction.

Boxed Warning:

Risk of serious dehydration in pediatric patients.

Warnings/Precautions:

Avoid use in patients 6–<18yrs of age. Suspend dosing and rehydrate if severe diarrhea occurs. Pregnancy. Nursing mothers.

Pharmacological Class:

Guanylate cyclase-C agonist.

Adverse Reactions:

Diarrhea (may be severe), sinusitis, URTI, abdominal distension/tenderness, flatulence, increased liver enzymes, nausea, nasopharyngitis, UTI, dizziness.

Generic Availability:

NO

How Supplied:

Tabs—30

TRULANCE 30 tablets of 3mg dose packs (Qty:1)

appx. price $406.00