Patients who received gastric bypass surgery had lower rates of diabetic neuropathy at follow up that remained stable throughout the study.
In multivariate analyses, adverse late cranial ultrasound findings (CUS) were an independent risk factor for full scale IQ scores 70 (FSIQ 70). Adverse late cranial ultrasound findings and adverse findings on MRI were independent risk factors for moderate-to-severe disability (MTSD).
The majority of buprenorphine exposures in children 19 years and younger reported to the National Poison Data System (NPDS) were among children 6 years old and unintentional. However, the majority of exposures among adolescents aged 13 to 19 years were intentional and more commonly involved multiple substances.
A meta-analysis of 18 studies examining the association of prenatal antidepressant exposure with motor development in children showed a small overall effect of worse motor development outcomes among children exposed to antidepressants in pregnancy.
In this qualitative study, active failures in infectious agent transmission precaution practices were observed frequently.
In this study of the patterns of physical activity in adolescents and young adults, young age, white race, and higher income were all associated with greater physical activity.
Lack of superiority of rivaroxaban for secondary prevention of embolic stroke of undetermined source
At a median follow-up of eleven months, rivaroxaban was not superior to aspirin for prevention of secondary stroke after an initial primary embolic stroke of undetermined source.
Demographic data, such as larger birth weight and female gender, of infants born at 23 weeks' gestation were shown to influence the chance that active resuscitation was initiated.
In this cross-sectional study, the use of medications with depression as an adverse effect was associated with a higher prevalence of depression while a similar association was not observed for medications without depression as a possible side effect.
In this meta-analysis, there was no significant difference between lower and higher oxygen saturation targets on a primary composite of mortality or major disability at a corrected age of 18-24 months for infants born extremely preterm.
In this randomized controlled trial, there was no difference in the self-reported disability 12 months after injury between patients treated with negative pressure wound therapy (NPWT) and those treated standardardly.
In a review of children who presented to a specialist hematology clinic with isolated mild or moderate low platelet counts, though causes were variable, most required no interventions.
The use of recombinant human pentraxin 2 vs placebo resulted in a slower decline in lung function over 28 weeks for patients with idiopathic pulmonary fibrosis.
Goals-of-care (GOC) discussions were linked to improved patient outcomes and reduction of intensity in end-of-life care. The current study demonstrated that a survey-based intervention for priming clinicians with communication strategies was linked to increase in the occurrence, documentation, and quality of GOC discussions.
Updated risk calculations suggest that fewer people should be classified within the high-risk category for CVD.
Increasingly restrictive state alcohol policies were associated with reduced odds that a crash fatality was alcohol related, both when blood alcohol levels were above and below the legal limit for driving in the USA (0.08%).
Patients with leg ulcers caused by superficial venous reflux treated with compression therapy experienced earlier time to healing if they were treated with early-ablation therapy and opposed to deferred-ablation.
Identified viral pathogens were not associated with asthma exacerbation severity, but were linked to increased treatment failure. Evidence Rating Level: 2 (Good).
Patients undergoing coronary artery bypass grafting (CABG) who received a radial-artery graft rather than a saphenous-vein graft (both groups also received an internal-thoracic-artery graft) experienced fewer major adverse cardiac events at a mean follow-up of 60 months.
Surveillance of adverse events after diphtheria-tetanus-acellular pertussis (DTaP) vaccine administration reported to the Vaccine Adverse Event Reporting System (VAERS) between 1991 and 2016 revealed no new or unexpected adverse events.
Extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) did not show a 60-day mortality benefit compared to conventional ventilation and ECMO rescue therapy.
Stroke patients with unknown time of stroke onset and DWI-FLAIR mismatch indicative of a stroke within the prior 4.5 hours who were randomized to alteplase were more likely to have a favorable outcome at 90 days than those receiving placebo.
All opioid misuse patterns examined had a positive association with opioid overdose and death.
Children born to adolescent mothers in the care of child protection services (CPS) were more likely to be taken into CPS care themselves when compared to other children in the first 2 years of life.
In healthy infants, there was no significantly increased risk for cardiovascular or metabolic events associated with propranolol use for treatment of infantile hemangioma.
Physicians report feeling moral distress over policies that force inadequate care based on immigration status
Physicians working in settings that provide emergency only hemodialysis (EOHD) reported higher rates of professional burnout.
Patients with the highest Aβ40 also had the worst non-ST-segment elevation acute coronary syndrome (NSTE-ACS) risk profile.
The Committee on Pediatric Emergency Medicine of the American Academy of Pediatrics (AAP) has published a statement in support of bystander CPR and AED training based on a review of their benefits in the public health literature.
A standard of practice and educational intervention aimed to reduce intravenous opioids in favor of subcutaneous route resulted in reduced frequency of intravenous opioids.
In this double-blind randomized controlled trial, weekly or monthly buprenorphine depot injections were non-inferior to daily sublingual buprenorphine/naloxone in maintaining no evidence of illicit opioid use at 24 weeks in outpatients with opioid use disorder (OUD).