Thrombectomy improves functional outcomes for imaging screened patients 6 to 16 hours after stroke

February 23, 2018

Patients presenting with ischemic stroke 6 to 16 hours after they were last known to be well had improved functional outcomes at 90 days if treated with thrombectomy and medical therapy compared to medical therapy alone.

Aspirin comparable to rivaroxaban for extended venous thromboembolism prophylaxis following arthroplasty

February 23, 2018

Patients initially treated with rivaroxaban following total knee or hip arthroplasty experienced similar rates of venous thromboembolism (VTE) regardless of continued rivaroxaban use or switching to aspirin for extended VTE prophylaxis.

Anthropometric failure in children related to intra-population variation in health determinants

February 23, 2018

Differences in health determinants within populations have a greater effect on anthropometric status of children than differences in population level health determinants in low- and middle-income countries (LMICs).

Influenza vaccine not associated with increased risk of epilepsy in children

February 15, 2018

No increased risk of incident epilepsy was seen among children who received influenza vaccination during the 2009-2010 influenza season in Norway.

Nusinersen improves motor function in children with later-onset spinal muscular atrophy

February 15, 2018

Intrathecal injections of nusinersen in pediatric later-onset spinal muscular atrophy (SMA) patients were associated with increased clinical motor function scores compared to sham treated patients.

No benefit of sodium bicarbonate or acetylcysteine for prevention of complications after angiography

February 15, 2018

Amongst patients undergoing angiography, neither sodium bicarbonate nor acetylcysteine were effective in preventing a composite outcome of death, need for dialysis, or persistent kidney injury.

ICD placement in CKD patients increases hospitalizations without survival benefit

February 13, 2018

Adults with chronic kidney disease (CKD) and heart failure with reduced LVEF who received implantable cardioverter defibrillators (ICDs) did not differ from matched non-ICD patients with relation to all-cause mortality.

Quality of care for transient ischemic attack and minor stroke vary across country

February 13, 2018

In this study about quality of care for patients with TIA or minor stroke, there was substantial variation in adherence to guidelines for patients treated at Veteran's Affairs (VA) hospitals across the country.

Differences in sudden unexpected infant death rates reported between states

February 12, 2018

National sudden unexpected infant death (SUID) rates had the steepest decline during the 1990 to 1998 study time period, followed by slower decline during 1999 to 2015.

Mogamulizumab is safe and possibly effective in HTLV-1-associated myelopathy

February 12, 2018

In this combined phase 1-2a study, mogamulizumab used for treatment of human T-lymphotropic virus type 1 (HTLV-1) associated myelopathy was safe and associated with improvement in biomarkers of disease, as well as improvements in spasticity and motor disability.