Researchers found that up-front total thyroidectomy was performed in 61% of patients before the 2015 American Thyroid Association guidelines were implemented and in 31.4% after guideline implementation (odds ratio [OR], 0.29).
First trimester exposure to anytithyroid drugs (ATDs) was associated with a greater risk of congenital malformations, especially for pregnant women who were given prescriptions for methimazole (MMI) or both MMI and propylthiouracil (PTU).
The prevalence of malformations was 7.27 versus 5.94% in exposed offspring versus offspring of women who were not prescribed ATDs during pregnancy.
Those with moderate-to-severe deficiency (iodine-creatinine ratios <50 μg/g) had a 46% reduction in fecundity versus those whose iodine-creatinine ratios were in the adequate range (adjusted fecundability odds ratio of becoming pregnant per cycle, 0.54).
"Periodic screening and monitoring of CBC while on treatment is crucial to monitor development of neutropenia which can be totally asymptomatic," the authors concluded.
The Task Force that authored the Society's statement aimed to review the different forms of endocrine hypertension, focusing on prevalence, clinical presentation, recommendations on when to perform case detection testing, and available case-detection tests.
Subclinical hypothyroidism, hypothyroxinemia tx in pregnancy not linked to improved outcomes
Treatment of subclinical hypothyroidism in pregnancy may not always be the best option, according to a study published online Jan. 25 in The BMJ.
The American Thyroid Association (ATA) has released new evidence-based recommendations to guide clinicians in diagnosing and managing thyroid disease during pregnancy and the postpartum period.
Higher levels of free thyroxine (FT4) may indicate a greater risk of sudden cardiac death, even if those levels aren't abnormally high, according to a study published in the September 6 issue of Circulation.
Mission Pharmacal announced that the Food and Drug Administration (FDA) has approved its Abbreviated New Drug Application (ANDA) for over-the-counter liquid Potassium Iodide Oral Solution for use in the event of a nuclear emergency.
Hypothyroidism may increase risk for type 2 diabetes, even if thyroid hormone levels are kept within normal range, according to findings presented at the annual meeting of the The Endocrine Society.
The Endocrine Society has issued a statement advising clinicians to avoid administering compounded hormone medications to treat menopausal symptoms, female sexual dysfunction, and other hormone conditions.
Patients who have their thyroidectomy performed by a surgeon who does more than 25 such procedures a year tend to have fewer complications, according to a study published online in the Annals of Surgery.
This case report describes the first documented case of reversible, fluoxetine-induced hyperthyroidism in a patient after 10 weeks of treatment.
Data from a recent study suggest a potential relevant decrease in the risk of relapse when immunosuppressants are added to standard treatment of Graves' disease.
The use of certain antiepileptic drugs (AEDs) may cause alterations in thyroid hormone levels in patients with epilepsy.
Novartis' Afinitor (everolimus) has been approved by the Food and Drug Administration (FDA) for the treatment of patients with progressive, well-differentiated non-functional, neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin with unresectable, locally advanced or metastatic disease.
Women with hyperthyroidism have increased breast cancer risk, while hypothyroidism is associated with decreased risk, according to a study published in the European Journal of Endocrinology.
In the elderly, subclinical hypothyroidism is not associated with significantly increased risk of recurrent venous thromboembolism (rVTE), according to research published online in the Journal of Thrombosis and Haemostasis.
The United States Preventive Services Task Force (USPSTF) released its annual Report to Congress reporting on 5 high-priority evidence gaps regarding women's health.