Thyroid Disease

Hypothyroidism Treatment No Longer Available

By December 07, 2018

The manufacturing discontinuation was a business decision made by the Company.

Cancer Development Linked to Increased Diabetes Risk

June 11, 2018

In the first 2 years after cancer diagnosis, the excess risk for diabetes was highest, and it remained elevated throughout follow-up.

Hypoparathyroidism Treatment Granted Orphan Drug Designation

By June 07, 2018

TransCon PTH is a long-acting prodrug of parathyroid hormone designed to restore PTH to physiologic levels, normalizing blood and urinary calcium levels, serum phosphate levels and bone turnover.

Thyroidectomy Rates Lower After Guideline Implementation

April 02, 2018

Researchers found that up-front total thyroidectomy was performed in 61% of patients before the 2015 American Thyroid Association guidelines were implemented and in 31.4% after guideline implementation (odds ratio [OR], 0.29).

Antithyroid Drug Exposure in Early Pregnancy May Up the Risk for Congenital Malformations

January 23, 2018

The prevalence of malformations was 7.27 versus 5.94% in exposed offspring versus offspring of women who were not prescribed ATDs during pregnancy.

Iodine Deficiency May Impact Fertility in Women of Childbearing Age

January 16, 2018

Those with moderate-to-severe deficiency (iodine-creatinine ratios <50 μg/g) had a 46% reduction in fecundity versus those whose iodine-creatinine ratios were in the adequate range (adjusted fecundability odds ratio of becoming pregnant per cycle, 0.54).

Congenital Adrenal Hyperplasia Treatment Granted Orphan Drug Status

By December 07, 2017

CAH is a rare endocrine disorder caused by genetic mutations which result in an inability to produce cortisol.

Regular Thyroxine Use May Raise Thyroid Cancer Risk

July 31, 2017

Compared with controls, cases were more likely to have been previously diagnosed with hypothyroidism (adjusted odds ratio, 3.01).

Antithyroid Drug Induces Rare, Dangerous Side Effect

By May 11, 2017

"Periodic screening and monitoring of CBC while on treatment is crucial to monitor development of neutropenia which can be totally asymptomatic," the authors concluded.

USPSTF Issues Recommendation on Thyroid Cancer Screening

May 10, 2017

U.S. Preventive Services Task Force reaffirms guidelines it issued in 1996 and 2016

Endocrine Hypertension Screening Statement Released

By April 07, 2017

The Task Force that authored the Society's statement aimed to review the different forms of endocrine hypertension, focusing on prevalence, clinical presentation, recommendations on when to perform case detection testing, and available case-detection tests.

Avoid Washing Down Levothyroxine with This Drink

By April 03, 2017

Significantly lower total T4 absorption was noted.

Does Treating Subclinical Thyroid Disease During Pregnancy Improve Cognitive Outcomes in Children?

March 02, 2017

Subclinical hypothyroidism, hypothyroxinemia tx in pregnancy not linked to improved outcomes

FDA Approves Liquid Formulation of Levothyroxine

By February 15, 2017

The FDA have approved Tirosint-SOL, a liquid form of levothyroxine; a synthetic form of the thyroid hormone thyroxine.

Safety of Subclinical Hypothyroid Tx During Pregnancy Questioned

January 27, 2017

Treatment of subclinical hypothyroidism in pregnancy may not always be the best option, according to a study published online Jan. 25 in The BMJ.

ATA: Guidelines on Thyroid Disease Management During Pregnancy, Postpartum

By January 06, 2017

The American Thyroid Association (ATA) has released new evidence-based recommendations to guide clinicians in diagnosing and managing thyroid disease during pregnancy and the postpartum period.

USPSTF Issues Statement on Thyroid Cancer Screening

November 23, 2016

Widespread routine thyroid cancer screening can lead to overdiagnosis, overtreatment

Free Thyroxine Hormone Levels Linked to Sudden Cardiac Death

September 08, 2016

Higher levels of free thyroxine (FT4) may indicate a greater risk of sudden cardiac death, even if those levels aren't abnormally high, according to a study published in the September 6 issue of Circulation.

Difference of Opinion: Managing Subclinical Hypothyroidism

June 07, 2016

Physicians present cases for and against treatment for a 60-year-old patient

OTC Anti-Radiation Drug Gets FDA Approval

By May 17, 2016

Mission Pharmacal announced that the Food and Drug Administration (FDA) has approved its Abbreviated New Drug Application (ANDA) for over-the-counter liquid Potassium Iodide Oral Solution for use in the event of a nuclear emergency.

Dietary Supplement Use Leads to a Diagnosis of Thyrotoxicosis

By April 08, 2016

This case details the potential dietary supplement adverse effect, thyrotoxicosis.

Type 2 Diabetes Risks Increase With Hypothyroidism, Even With Low TSH

April 04, 2016

Hypothyroidism may increase risk for type 2 diabetes, even if thyroid hormone levels are kept within normal range, according to findings presented at the annual meeting of the The Endocrine Society.

Avoid Compounded Hormone Meds for Menopausal Sx - Endocrine Society

By April 01, 2016

The Endocrine Society has issued a statement advising clinicians to avoid administering compounded hormone medications to treat menopausal symptoms, female sexual dysfunction, and other hormone conditions.

Thyroid Removal Outcomes for Experienced vs. Non-Experienced Surgeons

March 28, 2016

Patients who have their thyroidectomy performed by a surgeon who does more than 25 such procedures a year tend to have fewer complications, according to a study published online in the Annals of Surgery.

Drug-Induced Thyroid Dysfunction in Depressed Patient

By March 23, 2016

This case report describes the first documented case of reversible, fluoxetine-induced hyperthyroidism in a patient after 10 weeks of treatment.

Risk of Graves' Disease Relapse May Be Reduced by Adding Immunosuppressants

By March 17, 2016

Data from a recent study suggest a potential relevant decrease in the risk of relapse when immunosuppressants are added to standard treatment of Graves' disease.

For Patients on AEDs, Clinicians Should Pay Attention to Thyroid Function

By March 08, 2016

The use of certain antiepileptic drugs (AEDs) may cause alterations in thyroid hormone levels in patients with epilepsy.

Afinitor Receives Additional FDA Approval

By February 26, 2016

Novartis' Afinitor (everolimus) has been approved by the Food and Drug Administration (FDA) for the treatment of patients with progressive, well-differentiated non-functional, neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin with unresectable, locally advanced or metastatic disease.

Contrasting Data on Thyroid Function-Breast Cancer Link

February 17, 2016

Women with hyperthyroidism have increased breast cancer risk, while hypothyroidism is associated with decreased risk, according to a study published in the European Journal of Endocrinology.