Thromboembolic Disorders

FDA: Antibiotic Linked to Increased Risk of Death in Heart Disease Patients

By February 22, 2018

The Agency is asking healthcare professionals to use caution before prescribing the antibiotic to this patient population.

Cardiovascular Risk Compared Among COX-2 Selective, Nonselective NSAIDs

By February 22, 2018

Results showed the crude hazard ratio (HR) of major cardiovascular events was 1.99 (95% CI, 1.28-3.09) for COX-2 vs. nonselective NSAIDs.

Retinal Images Can Be Used to Predict CV Risk, Says Google Study

By February 22, 2018

The model used retinal images to predict cardiovascular risk.

Treatment Window for Using Clot Retrieval Device Now Expanded

By February 15, 2018

The Trevo device is inserted via a catheter into the blood vessel to the site of the clot. The end portion of the device expands (up to 3-6mm diameter) and grips the clot, allowing the physician to pull it back through the vessel along with the device.

FDA: New Clinical Decision Support Tool Helps ID Stroke Sooner

By February 14, 2018

The Viz.AI Contact application is a computer-aided triage software that uses an artificial intelligence algorithm to analyze images for indicators associated with a stroke.

Quality of care for transient ischemic attack and minor stroke vary across country

February 13, 2018

In this study about quality of care for patients with TIA or minor stroke, there was substantial variation in adherence to guidelines for patients treated at Veteran's Affairs (VA) hospitals across the country.

Safety, Efficacy of Direct Oral Anticoagulants + Antiplatelets Evaluated After ACS

February 12, 2018

Pronounced benefit for patients with STEMI, but no significant effect for patients with NSTE-ACS

Preoperatively diagnosed patent foramen ovale linked to increased perioperative stroke risk

February 08, 2018

A preoperatively diagnosed patent foramen ovale was associated with an increased risk of stroke within 30 days of non-cardiac surgery. With Evidence Rating Level: 2 (Good).

Women May Experience Worse Stroke Outcomes Than Men

February 08, 2018

The researchers found that in 8 studies which included ischemic and hemorrhagic stroke, women had worse outcomes than men, with significantly lower odds of good outcome or increased odds of poor outcome.

PFO Could Increase Stroke Risk Following Non-Cardiac Surgery

February 07, 2018

There were 850 ischemic strokes (0.6%) within 30 days of surgery: 3.2 and 0.5% among patients with and without PFO, respectively.

Hand Breaking May Be Best for Splitting Aspirin Tablets

February 02, 2018

There was a statistically significantly smaller loss of mass (mg) for the hand (P<0.001) and the PillTool (P<0.001) versus the knife and the Pilomat.

Migraines and Cardiovascular Disease: What's the Link?

February 01, 2018

There were positive associations for migraine with myocardial infarction, ischemic stroke and hemorrhagic stroke, venous thromboembolism, and atrial fibrillation or flutter.

Should all Syncope Patients Undergo Evaluation for Pulmonary Embolism?

January 30, 2018

At 90 days, the prevalence of venous thromboembolism varied from 0.3 to 1.37% for all patients and from 0.75 to 3.86% for hospitalized patients.

Stroke, Major Bleed Risk Compared Among Novel Oral Anticoagulants

By January 26, 2018

The study analyzed data from NVAF patients newly initiating treatment with dabigatran, rivaroxaban or apixaban.

Combo Tx Cuts Stroke Risk More Than BP, Cholesterol Drugs Alone

By January 25, 2018

The Heart Outcomes Prevention Evaluation Study was a large, international study involving over 12,000 patients from 21 countries.

Study Examines Light Smoking Impact on Heart Disease, Stroke Risk

January 25, 2018

The researchers found that the pooled relative risk for coronary heart disease was 1.48 and 2.04, respectively, for smoking 1 and 20 cigarettes per day for men.

Endovascular Thrombectomy Examined at 6 to 16 Hours After Stroke

January 25, 2018

Higher percentage of patients functionally independent at 3 months with endovascular therapy

ASA: Rise in Spontaneous Strokes During Pregnancy Needs More Attention

January 25, 2018

"We need to increase awareness in the medical community about the increasing trend of spontaneous subarachnoid hemorrhage in pregnancy because management of these patients continues to be a clinical conundrum," study lead author Kaustubh Limaye, MD.

Majority of Stroke Patients Referred to Rehab Do Not Receive Services

January 25, 2018

Non-white patients may have reduced odds of receiving timely outpatient rehabilitation therapy

FDA Approves Ready-to-Use Bivalirudin Formulation

By January 22, 2018

Premixed formulations can help simplify the preparation process and avoid errors associated with compounding medications.

New Guidelines Available on Anticoagulation Tx for Cardiopulmonary Bypass

January 22, 2018

Recommendations for heparin dosing and monitoring, contraindications and alternatives, reversal

Percutaneous patent foramen ovale closure is superior to medical treatment alone in preventing recurrent stroke

January 19, 2018

Patent foramen ovale (PFO) closure was superior to medical treatment alone in preventing transient ischemic attack (TIA) and recurrent stroke.

Does Pharmacist Presence in Stroke Response Cut Door-to-Needle Time?

January 19, 2018

Overall, 71 and 29% of patients in the PharmD and no-PharmD groups met the goal of DTN ≤60 minutes (P<0.01).

No New Concerns With Rivaroxaban, According to FDA Mini-Sentinel Assessment

By January 16, 2018

The FDA analysis evaluated the safety of Xarelto in people with nonvalvular atrial fibrillation who initiated Xarelto or warfarin from November 2011 to April 2015.

Device closure for patent foramen ovale decreases recurrent stroke risk compared to medical therapy alone

January 16, 2018

Transcatheter device closure for patent foramen ovale (PFO) decreased recurrent stroke risk compared to medical therapy alone.

Thrombosis Risk Examined in Myeloproliferative Neoplasms

January 16, 2018

The researchers found that, compared with control participants, for patients with MPNs, the hazard ratios for arterial thrombosis were 3.0, 2.0, and 1.5 at 3 months, 1 year, and 5 years, respectively.

Recall: Clopidogrel Bottles May Contain Simvastatin Tablets

By January 10, 2018

International Laboratories, LLC is notifying distributors and customers by letter and is arranging for return of all recalled products.

Delta CHA<sub>2</sub>DS<sub>2</sub>-VASc May Forecast Stroke Likelihood More Accurately

January 09, 2018

The Delta CHA2DS2-VASc score significantly better predicted ischemic stroke compared to baseline or follow-up CHA2DS2-VASc scores

Are Patients With ITP at Increased Risk for Cardiovascular Disease?

January 09, 2018

The elevated risk of developing CVD in the ITP cohort (adjusted incidence rate ratio [IRR], 1.38) remained even after a sensitivity analysis which included only incident cases of ITP.

Survival in Patients With Severe Aortic Stenosis Impacted by LVEF

January 05, 2018

Compared with LVEF ≥70%, LVEF <50% and 50 to 59%, but not 60 to 69%, were independently associated with poorer outcomes in the conservative group.