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Bleeding disorders
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Generic Name and Formulations:

Thrombin [bovine origin] 5000 IU, 20000 IU; per vial; pwd for topical use after reconstitution; preservative-free.


Pfizer Inc.

Select therapeutic use:

Indications for THROMBIN-JMI:

Aid to hemostasis for oozing blood and minor bleeding from accessible capillaries and small venules. Adjunct for surgical hemostasis with absorbable gelatin sponge.


For topical use only. See literature. Profuse bleeding (eg, abraided surfaces of liver or spleen): 1000 IU/mL. General use (eg. plastic surgery, dental extractions, skin grafting): 100 IU/mL. May dilute to prepare intermediate strengths, if needed. Oozing surfaces: may use dry form.


Not recommended.


Not for injection or use in large blood vessels. Antibody formation: do not re-expose, abnormalities in hemostasis (eg, severe bleeding or thrombosis) more likely with repeated use. Pregnancy (Cat.C). Nursing mothers.

Pharmacological Class:

Topical hemostatic.

Adverse Reactions:

Hypersensitivity reactions, antibody formation.

How Supplied:

Vials—1 (w. diluent)
Pump Spray Kit (20000 IU)—1 (w. diluent)
Syringe Spray Kit (20000 IU)—1 (w. diluent)
Epistaxis Kit (5000 IU)—1 (w. diluent)