Women's Health Archives - MPR

Women’s Health

Pregnancy-Related Adverse Events Linked to Isotretinoin Persist Despite REMS Implementation

According to the findings of a recent retrospective analysis, pregnancy and pregnancy-related adverse events related to isotretinoin administration have dropped since the initiation of the iPLEDGE program by the Food and Drug Administration (FDA) in 2006, however reports of fetal exposure persist.  The iPLEDGE program is a Risk Evaluation and Mitigation Strategy (REMS) that aims…