CDC Plans Cellphone COVID-19 Vaccine Tracking System
Health checks will be done by text messages and email every day during the first week after vaccination.
Viral Infections
Convalescent Plasma Has Limited Benefit for Moderate COVID-19
Randomized phase II trial shows no drop in progression to severe disease, all-cause deaths.
FDA Approves Veklury as First Treatment for COVID-19
The FDA approved Veklury (remdesivir; Gilead Sciences) for the treatment of COVID-19 in patients aged ≥12 years (weighing ≥40kg) requiring hospitalization.
MPR Weekly Dose Podcast Episode 55
Results from the survey assessing willingness to receive a COVID vaccine; Dr. Fauci shares that he is ‘cautiously optimistic’ a vaccine could arrive before year’s end; And the breaking news that remdesivir (Veklury) has gained FDA approval.
Moderna: 30,000 Participants Enrolled in COVID-19 Vaccine Trial
The trial is investigating the efficacy, safety, and immunogenicity of mRNA-1273 at the 100mcg dose.
CDC: Number of COVID-19 Deaths May Be Underreported
Only two-thirds of the nearly 300,000 excess deaths in 2020 are attributed to COVID-19.
Tocilizumab Does Not Prevent Intubation, Death in COVID-19
Intubation or death, disease worsening similar for tocilizumab, placebo in hospitalized patients.
Survey Reveals Factors Contributing to COVID-19 Vaccine Acceptance
To estimate the association between attribute level and probability of choosing and receiving a vaccine, the study authors calculated the average marginal component effects sizes as well as marginal means.
Scientists to Infect Volunteers With COVID-19 in Challenge Trial
Challenge trials have long history, going back to development of smallpox vaccine in 1796.
NIH: Immune Modulators to Be Investigated for COVID-19
The NIH-led trial will assess 3 drugs: infliximab, a tumor necrosis factor blocker, abatacept, a selective T cell costimulation modulator, and cenicriviroc, an investigational immunomodulator that blocks 2 chemokine receptors, CCR2 and CCR5.
