Trial Investigating COVID-19 Therapy in Long-Term Care Facilities Begins
The BLAZE-2 trial is being conducted in collaboration with the NIAID and the COVID-19 Prevention Network.
Viral Infections
DNA-Based Therapy Gets Orphan Drug Status for Recurrent Respiratory Papillomatosis
The FDA has granted Orphan Drug designation to INO-3107, a DNA plasmid immunotherapy, for the treatment of recurrent respiratory papillomatosis, a rare disease caused by human papillomavirus types 6 and 11 infections.
Intravenous Vitamin C Linked to Early Recovery in Critically Ill COVID-19 Patient
The patient, a 74-year-old female, presented to the ER after experiencing a low grade fever, cough, and shortness of breath for 2 days.
Young Children Have Higher Amounts of SARS-CoV-2 RNA
Children younger than 5 years have lower median cycle threshold values compared with older children, adults
No Benefit With Tocilizumab in COVID-19 Pneumonia Trial
A phase 3 study of tocilizumab (Actemra®) for the treatment of hospitalized patients with severe COVID-19 pneumonia did not meet its primary and key secondary end points.
COVID-19 Vaccine Candidate Provides Protection in Animal Challenge Study
Vaccination with mRNA-1273, Moderna’s coronavirus disease 2019 (COVID-19) vaccine candidate, led to robust immune responses and protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in nonhuman primates.
Respiratory Sampling Strategies for Detecting SARS-CoV-2 Compared
Sputum sampling was found to be a valuable method for diagnosing and monitoring patients with coronavirus disease 2019 (COVID-19), according to a recent systematic review and meta-analysis published in EBioMedicine.
Pfizer, BioNTech Select COVID-19 Vaccine Candidate, Initiate Phase 2/3 Study
Pfizer and BioNTech have selected a coronavirus disease 2019 (COVID-19) vaccine candidate and have initiated their phase 2/3 safety and efficacy trial.
COVID-19 Can Result in Prolonged Illness Even in Milder Cases
At median of 16 days from testing date, 35 percent report not having returned to usual state of health.
COVID-19 Patients With Elevated CRP May Benefit From Steroid Therapy
The observational study, which was led by the Albert Einstein College of Medicine and Montefiore Health System, aimed to assess the effect of glucocorticoid therapy on mortality and the need for mechanical ventilation in hospitalized patients with COVID-19.
