Algorithm Predicts Urinary Tract Infection Without Microscopy
Authors say the new algorithm could be used to safely withhold antibiotics in low-risk patients in the primary care setting
Diagnosis & Disease Information
Trimethoprim-Sulfamethoxazole vs Amoxicillin Ups Hyperkalemia Risk
Trimethoprim-sulfamethoxazole is mostly excreted through the kidneys, and it can cause hyperkalemia by reducing potassium excretion.
Cefepime/Enmetazobactam Noninferior for Complicated UTI
Cefepime/enmetazobactam is noninferior and superior to piperacillin/tazobactam for clinical cure and microbial eradication
Inappropriate Antibiotic Prescribing for Uncomplicated Cystitis Still Occurs
Urologists appear more likely than other specialists to inappropriately treat uncomplicated cystitis, according to study findings.
Higher Fluoroquinolone Doses May Be Toxic in Advanced CKD
Guidelines recommend that clinicians prescribe fluoroquinolone at lower doses in patients with reduced kidney function.
June 2022 Recap: Drug Pipeline Updates
Stay up-to-date on the latest drugs in development.
FDA Needs More Data on Tebipenem HBr for Complicated UTI
In the CRL, the FDA stated that the application could not be approved in its present form and that an additional clinical trial would be required.
Zerbaxa Approved for Complicated Pediatric Intra-abdominal, Urinary Tract Infections
The approvals were based on data from pediatric trials evaluating treatment for complicated intra-abdominal infections and complicated urinary tract infections.
Oral Tebipenem Effectively Treats Complicated UTI, Pyelonephritis
Tebipenem pivoxil hydrobromide is an orally bioavailable carbapenem with activity against uropathogenic Enterobacterales.
SGLT2 Inhibitors for Diabetes May Protect Against AKI, Increase UTI Risk
Providers need to assess the benefit-risk profile of SGLT2 inhibitors for individual patients, and take steps to avoid unnecessary risks.
