Inappropriate Antibiotic Prescribing for Uncomplicated Cystitis Still Occurs
Urologists appear more likely than other specialists to inappropriately treat uncomplicated cystitis, according to study findings.
Urinary Tract Infection
Higher Fluoroquinolone Doses May Be Toxic in Advanced CKD
Guidelines recommend that clinicians prescribe fluoroquinolone at lower doses in patients with reduced kidney function.
June 2022 Recap: Drug Pipeline Updates
Stay up-to-date on the latest drugs in development.
FDA Needs More Data on Tebipenem HBr for Complicated UTI
In the CRL, the FDA stated that the application could not be approved in its present form and that an additional clinical trial would be required.
Zerbaxa Approved for Complicated Pediatric Intra-abdominal, Urinary Tract Infections
The approvals were based on data from pediatric trials evaluating treatment for complicated intra-abdominal infections and complicated urinary tract infections.
Oral Tebipenem Effectively Treats Complicated UTI, Pyelonephritis
Tebipenem pivoxil hydrobromide is an orally bioavailable carbapenem with activity against uropathogenic Enterobacterales.
SGLT2 Inhibitors for Diabetes May Protect Against AKI, Increase UTI Risk
Providers need to assess the benefit-risk profile of SGLT2 inhibitors for individual patients, and take steps to avoid unnecessary risks.
Nonantibiotic Prophylaxis Noninferior for Recurrent UTI
Incidence of antibiotic-treated UTI during 12-month treatment period noninferior for methenamine hippurate versus prophylactic antibiotics
Cefepime-Taniborbactam Bests Meropenem in Complicated UTI Trial
The phase 3 CERTAIN-1 study compared the efficacy and safety of cefepime-taniborbactam to meropenem in 661 adults with cUTI.
MV140 Vaccine May Prevent Recurrent Urinary Tract Infections
MV140 is a sublingual vaccine of whole-cell inactivated bacteria that may be an alternative to frequent antibiotics for recurrent urinary tract infections.
