Compared with standard of care tests and most clinical signs, the molecular bacterial load assay demonstrated higher sensitivity and more rapid turnaround times for monitoring tuberculosis treatment.
Positive results with respect to the presence of latent tuberculosis infection in patients with renal failure were more consistent with the use of QuantiFERON-TB Gold Plus testing compared with the use of QuantiFERON-TB Gold In-Tube testing.
Guidelines include preplacement TB risk assessment, postexposure symptom evaluation and testing
Number of cases, disease incidence decreased globally, but more progress needed to meet targets
A short regimen is noninferior to a long regimen for patients with rifampin-resistant tuberculosis that is susceptible to fluoroquinolones and aminoglycosides, according to a new study.
The researchers found that a baseline smear grade of 3+ relative to <2+, HIV seropositivity and adherence of ≤90% were significant risk factors for an unfavorable outcome
The patient, a 42-year-old female with systemic lupus erythematosus treated with mycophenolate mofetil and prednisone, reported swelling and pain in the fifth finger of her left hand for about 1-week.
The researchers found that the mean MIC of isoniazid below the breakpoint was 0.0334 ± 0.0085µg/mL and 0.0286 ± 0.0092µg/mL in the relapse and cure groups, respectively.
Rifampin has advantage of being a shorter, single-drug regimen that is palatable for children
In 2017, a Work Group was assembled to conduct a systematic review of 3HP regimen studies published between January 2006 to June 2017, specifically looking at outcomes in children, individuals with HIV/AIDS, and those who self-administered treatment.
