The Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for ZTlido® (lidocaine topical system; Scilex Pharmaceuticals) to include additional administration-related data. ZTlido is indicated for the relief of pain associated with postherpetic neuralgia in adults. The product is available as a single-layer, drug-in-adhesive topical delivery system containing 36mg of lidocaine in a…
“In context of the recent rise in supply and demand of compounded preparations, lack of evidence regarding systemic absorption of ingredients used in compounded topical pain creams gives rise to a substantial public health concern,” the authors concluded.
Perrigo announced that the FDA has approved the abbreviated New Drug Application for its over-the-counter diclofenac sodium topical gel 1% for the temporary relief of arthritis pain in the hand, wrist, elbow, foot, ankle or knee in adults ≥18 years old.
Diclofenac sodium topical gel and olopatadine HCl ophthalmic drops will soon be available over-the-counter (OTC) after the the Food and Drug Administration (FDA) switched the status of these products from prescription to nonprescription.
To investigate the effectiveness of compounded creams in the treatment of chronic pain conditions, study authors performed a double-blind, randomized, parallel study comparing creams compounded with an active ingredient to placebo creams.
The non-aqueous adhesive patch requires 36mg per topical system to achieve the same therapeutic dose as Lidoderm (lidocaine 5%) which contains 700mg per patch.
The Agency is urging manufacturers to stop marketing OTC oral drug products containing benzocaine for teething to this patient population.
The analysis evaluated changes in opioid use, other concurrrent medication use, and pain severity and interference in opioid-experienced patients
The new Convenience Pack includes SuturaGel Methylcellulose Base, which is designed to reduce the amount of medication run-off from the treatment area.
An overall lack of quality evidence exists for the use of topical analgesics and anesthetics (creams, gels and patches) as a therapeutic method for treating chronic pain, according to a new review published in the journal Dermatitis.
