IV Vitamin C Increases Risk for Death, Organ Failure in Sepsis
Risk increased with intravenous vitamin C versus placebo for adults with sepsis in the ICU receiving vasopressor therapy
Risk increased with intravenous vitamin C versus placebo for adults with sepsis in the ICU receiving vasopressor therapy
To what extent does hospital fluid culture influence the mortality rates of patients with severe sepsis and septic shock?
In patients with sepsis admitted to the ICU who were classified as obese experienced longer durations of ventilator use and had a higher risk for ARDS compared with patients with a normal BMI.
Combination of vitamin C, hydrocortisone, thiamine not superior to usual care with hydrocortisone alone.
Statin therapy before septic shock may decrease the risk for acute respiratory distress syndrome.
The Food and Drug Administration (FDA) has granted Fast Track designation to nangibotide (LR12; Inotrem S.A.) for the treatment of septic shock. Nangibotide, a TREM-1 (triggering receptor expressed on myeloid cells-1) inhibitor, is a chemically synthesized peptide that acts as a decoy receptor interfering with the binding of TREM-1 and its ligand. Based on preclinical…
Doctors diagnosed Manteufel with a rare blood infection caused by Capnocytophaga canimorsus, which is commonly found in the saliva of most healthy dogs and is usually not harmful to humans, the Post reported.
Giapreza, a vasoconstrictor, increases blood pressure through increased aldosterone release
Death rates for the hydrocortisone group was not significantly lower than the placebo group; a total of 511 patients (27.9%) in the hydrocortisone group died compared to 526 (28.8%) in the placebo group (odds ratio, 0.85; 85% CI, 0.82 to 1.10; P=0.50).
Data on renal function, need for RRT, timing of hemodialysis catheter placement, and timing of RRT initiation were abstracted for 70 patients.