FDA Rejects Gefapixant NDA for Chronic Cough
The application includes data from the two phase 3 studies, which evaluated the efficacy and safety of gefapixant in adults with refractory or unexplained chronic cough for at least 1 year.
Respiratory Diseases/Disorders
Ryaltris Nasal Spray Approved for Seasonal Allergic Rhinitis
Ryaltris is a metered, fixed-dose nasal spray that delivers 665mcg of olopatadine hydrochloride and 25mcg of mometasone furoate in each spray.
Shorter Antibiotic Course Safe, Effective for Uncomplicated Childhood CAP
The randomized, double-blind, placebo-controlled study included a total of 380 patients aged 6 to 71 months with nonsevere CAP.
Secondhand Vape Exposure Linked to Respiratory Symptoms
Young adults with secondhand vape exposure have increased odds of bronchitic symptoms, shortness of breath
Tezspire Now Available for Treatment of Severe Asthma
Tezspire is a first-in-class human monoclonal antibody that works by blocking thymic stromal lymphopoietin, an epithelial cytokine involved in the initiation and persistence of airway inflammation.
Consuming Olive Oil May Reduce Mortality Risk in US Adults
Replacing butter, margarine, mayonnaise, dairy fat with olive oil linked to reductions in total, cause-specific mortality
Novel Immunomodulator Gets Orphan Drug Status for Sarcoidosis
Results from a phase 1/2 showed that ATYR1923 was safe and well tolerated.
Symptom Presentation Varies by SARS-CoV-2 Variant
During first wave of COVID-19, cough occurred first in the United States, while fever occurred first in China
Tezspire Approved as Add-On Maintenance Treatment for Severe Asthma
Tezspire is a first-in-class human monoclonal antibody that works by blocking thymic stromal lymphopoietin.
Strategies Compared for Ruling Out Pulmonary Embolism
Diagnostic strategies with pretest probability-dependent D-dimer thresholds have highest efficiency, highest predicted failure rate
