Fetroja Approved for Hospital-Acquired, Ventilator-Associated Bacterial Pneumonia
The FDA has approved Fetroja® (cefiderocol; Shionogi) for the treatment of adult patients with HABP/VABP caused by susceptible Gram-negative pathogens.
Respiratory Diseases/Disorders
Kalydeco Approval Expanded to Include Younger Cystic Fibrosis Patients
The approval was based on data from a phase 3 open-label safety study that included a cohort of 6 children 4 months to <6 months of age.
Perrigo Recalls All Albuterol Sulfate Inhalers
To date, Perrigo has received several thousand complaints related to their product.
AirDuo Digihaler, ArmonAir Digihaler Now Available for Asthma
The products contain a built-in electronic module that detects, records and stores data on inhaler events.
Tocilizumab Reduces Need for Mechanical Ventilation in COVID-19 Pneumonia Trial
Patients treated with tocilizumab were 44% less likely to progress to mechanical ventilation or death compared with placebo.
Baricitinib Plus Remdesivir Cuts Time to Recovery for Hospitalized COVID-19 Patients
The ACTT-2 study began on May 8 and included more than 1000 patients.
Benralizumab Looks Promising in Nasal Polyps Trial
The 56-week OSTRO trial evaluated the efficacy and safety of benralizumab, an interleukin-5 antagonist, in 413 adult patients with severe nasal polyposis.
Trelegy Ellipta Approved for Asthma Maintenance Treatment
Trelegy Ellipta combines fluticasone furoate, an inhaled corticosteroid with umeclidinium, an anticholinergic and vilanterol, a long-acting β2-adrenergic agonist.
Statistically Significant Reduction in Cough Frequency Observed in Gefapixant Trials
The double-blind, placebo-controlled studies, COUGH-1 and COUGH-2, included 730 and 1314 adult patients with refractory or unexplained chronic cough for at least 1 year, respectively.
AAP: Choosing Wisely Recs on Pediatric Pulmonology, Sleep Medicine
The list, titled “Five Things Physicians and Patients Should Question,” was developed by members of the AAP Section on Pediatric Pulmonology and Sleep Medicine.
