Combined Modalities Improve Survival in Stage III Inoperable NSCLC
This study tested the efficacy of singular and combined treatment modalities on survival in patients with inoperable, locally advanced non-small cell lung cancer (≥70 years).
Respiratory and Thoracic Cancers
Potential Med Errors Prompt FDA Action on Vinca Alkaloid Labeling
Chemotherapy agents such as vincristine sulfate injection, vinblastine sulfate injection, and vinorelbine tartrate injection should only be prepared in IV infusion bags.
Tiragolumab Gets Breakthrough Therapy Status for PD-L1-High NSCLC
Tiragolumab is a monoclonal antibody that works by binding to TIGIT, a protein receptor on immune cells, and blocking its interaction with the poliovirus receptor.
Tagrisso Approved as Adjuvant Therapy for Early-Stage EGFR-Mutant NSCLC
The approval was based on data from the double-blind, placebo-controlled phase 3 ADAURA study.
FDA Accepts and Grants Priority Review to New sBLA for Keytruda
Results presented at the European Society for Medical Oncology Virtual Congress 2020showed significant improvements in the primary endpoints for the pembrolizumab group.
New Dosing Option Approved for Imfinzi in NSCLC, Bladder Cancer
The approval was based on data from several clinical trials, including the phase 3 PACIFIC trial and the phase 3 CASPIAN trial.
Lorlatinib Superior to Crizotinib for ALK-Positive NSCLC
Interim analysis shows risk for disease progression or death lower for first-line therapy with lorlatinib versus crizotinib
Malignancies May Occur Earlier in Men vs Women After Sarcoidosis Diagnosis
In patients with sarcoidosis, cancer was found to develop earlier in men vs women.
Common Cardiovascular Drugs Associated With Reduced Lung Cancer Mortality
Aspirin, metformin, and statins were independently associated with decreased lung cancer mortality, according to a population-based study.
FDA Approves Blood-Based Test as Companion Diagnostic for Multiple Cancer Drugs
Using a blood sample, the test is able to analyze more than 300 cancer-associated genes for alterations.
