Secnidazole Under Review for Trichomoniasis
The sNDA is based on data from a phase 3 study that evaluated secnidazole in 147 adult female patients with trichomoniasis.
Protozoal Infections
Study Findings Support Use of Secnidazole for Trichomoniasis
Data from the pivotal phase 3 trial demonstrated clinically and statistically significant microbiological cure compared with placebo at the test of cure visit.
Lampit Approved for Chagas Disease in Pediatric Patients
Accelerated approval was based on the number of treated patients who became IgG antibody negative or who showed an at least 20% decrease in optical density on 2 different IgG antibody tests against antigens of T. cruzi.
Single-Dose Secnidazole Treats Trichomoniasis in Phase 3 Trial
The multicenter, double-blind, placebo-controlled study investigated the efficacy and safety of secnidazole in 147 adult females with trichomoniasis.
First Generic of Daraprim Gets FDA Approval
The Food and Drug Administration (FDA) has approved the first generic of Daraprim (pyrimethamine) tablets. Pyrimethamine, a folic acid antagonist, is indicated for the treatment of toxoplasmosis when used with a sulfonamide. The approved generic version of Daraprim has been granted to Cerovene Inc and will be supplied as 25mg tablets. Toxoplasmosis is a disease…
Miltefosine May Be Effective for Progressive Acanthamoeba Keratitis
This article is part of MPR’s coverage of the American Academy of Ophthalmology 2019 Meeting, taking place in San Francisco, CA. Our staff will report on medical research related to eye disorders, conducted by experts in the field. Check back regularly for more news from AAO 2019. SAN FRANCISCO – For patients with progressive Acanthamoeba…
Tap Water in Neti Pot Linked to Seattle Woman’s Death From Brain-Eating Amoeba
The Balamuthia mandrillaris amoeba got into her upper nasal cavity and then into her bloodstream, eventually reaching her brain, according to the study published in the December issue of the International Journal of Infectious Diseases.
Vectorborne Diseases Up More Than Two-Fold From 2004 to 2016
During 2004 to 2016, 82 percent of all tickborne disease reports were Lyme disease
First Tests to Screen for Babesiosis in Whole Blood, Plasma Approved
These tests are intended to screen samples from individual human donors, including volunteers who give whole blood and blood components, as well as living organ and tissue donors.
Miltefosine Gains Orphan Drug Status for Serious CNS Infections
Miltefosine is an alkyllysophospholipid analogue drug with in vitro activity against the promastigote and amastigote stages of Leishmania species. It is already approved to treat visceral, mucosal and cutaneous leishmaniasis in patients aged ≥12 years; it is the first oral treatment for this rare tropical parasitic disease.
