FDA Grants Orphan Drug Status to Live Biotherapeutic for Pouchitis
The FDA has granted Orphan Drug designation to EXE-346 (ExeGi Pharma) for the prevention of disease relapse in pouchitis.
Probiotics
Guideline Issued on the Use of Probiotics for Managing GI Disorders
Probiotics should only be recommended for specific patient populations since there is not enough evidence to support their use in the majority of digestive conditions, according to new clinical guidelines released by the American Gastroenterological Association (AGA) and recently published in Gastroenterology.
Online Information About Probiotics Often Unreliable
Most information from commercial sources; only 35 percent of webpages refer to scientific literature.
Safety Data May Be Lacking in Trials of Prebiotics, Probiotics, Synbiotics
Thirty-seven and 16% of the 242 studies mentioning harm-related results used only generic statements to describe AEs and used inadequate metrics, respectively.
L. reuteri Probiotic Effective for Colic in Breastfed Infants
Probiotic group averaged less crying and/or fussing time and was more likely to experience treatment success
Can Probiotics Prevent C. difficile-Associated Diarrhea?
Analysis of all patients who completed the study (N=8,672) found that probiotics reduce the risk of CDAD by 60%. Among the probiotic group the incident of CDAD was 1.5% (70/4,525) compared to 4% (164/4,147) in the placebo.
Does Probiotic Use Attenuate Depressive Symptoms?
An increasing body of research has demonstrated a strong connection between the gut microbiome and mood disorders.
Gripe Water with Probiotic Now Available for Infants
Wellements announced the launch of Wellements Probiotic Gripe Water, the first gripe water to contain probiotics, to help ease a newborn’s stomach discomfort often associated with gas, colic, fussiness, and hiccups.
Are Probiotics Beneficial for Rheumatoid Arthritis Patients?
Probiotic supplementation seems beneficial for patients with rheumatoid arthritis (RA), according to a study published online in the International Journal of Rheumatic Diseases.
Antibiotic Use in Youth May Up Adolescent Prediabetes Risk
Young children who take antibiotics may disrupt their gut microbes and be more likely to develop adolescent prediabetes.
