Once-Weekly Levomethadone Fast Tracked for Opioid Use Disorder
LYN-014 is an investigational oral, once-weekly, ultra-long-acting, extended-release levomethadone capsule to treat opioid use disorder.
Poisoning
Risk of Falsely Low Results Prompts Recall of Lead Tests
The FDA is concerned that obtaining falsely low test results may lead to inappropriate follow-up assessments, which may result in patient harm.
FDA to Review Buprenorphine Extended-Release Injection for Opioid Use Disorder
Brixadi (buprenorphine) is an investigational, extended-release weekly and monthly subcutaneous injection for moderate to severe opioid use disorder.
Guidelines Developed for Diagnosing, Treating Botulism
Signs and symptoms of some neurologic conditions overlap with botulism; thorough, serial neurologic exams should be conducted.
Anavip Approval Expanded to Include Copperhead, Cottonmouth/Water Moccasin Envenomations
Anavip contains venom-specific F(ab’)2 fragments of immunoglobulin G that bind and neutralize venom toxins.
Shortage of Lead Poisoning Treatment Announced
Chemet is an orally active, heavy metal chelating agent indicated for the treatment of lead poisoning in pediatric patients.
CDC: ~20% of US Adults Currently Use Tobacco Products
Prevalence of use higher for men, adults aged ≤65 years, uninsured, those with disability or limitation
2012 to 2018 Saw Substantial Rise in Naloxone Dispensing
Regional variation in naloxone dispensing considerable; rates lowest in most rural counties.
FDA: Opioid Med Labels Will Include More Info on Appropriate Tapering in Physically Dependent Patients
The Food and Drug Administration is requiring labeling changes for all opioid analgesics used in the outpatient setting, to provide additional guidance on safe opioid tapering.
FDA Updates REMS for Transmucosal Immediate-Release Fentanyl Products
The Food and Drug Administration has announced that the Risk Evaluation and Mitigation Strategy (REMS) for transmucosal immediate-release fentanyl (TIRF) medications has been updated to better ensure the safe use of these products.
