FDA: Mandatory Opioid Prescriber Education to Be Discussed at Upcoming Workshop
Overall opioid overdoses and opioid-involved deaths continue to increase.
Diagnosis & Disease Information
2019 to 2020 Saw Increase in Benzodiazepine Overdose ED Visits
Benzodiazepine deaths increased from April-June 2019 to April-June 2020, with larger increase for illicit benzodiazepine deaths
Opioid Tapering Tied to Higher Risk for Overdose, Mental Health Crisis
Rates of overdose, mental health crises increased after dose tapering among patients prescribed stable, long-term, higher-dose opioid therapy
Sodium Bicarbonate Injection Recalled Due to Microbial Contamination
According to the Company, intravenous administration of the affected product could lead to “site specific infections as well as serious systemic infections which may be life-threatening.”
MPR Weekly Dose Podcast Episode 88
The FDA authorizes a postexposure prophylaxis for COVID-19; A new treatment is okay’d for lupus; A higher dose naloxone nasal spray became available; The risk evaluation and mitigation program for Clozapine has had important changes, and finally, Istodax has had an indication withdrawn.
Kloxxado Now Available for Emergency Treatment of Opioid Overdose
Kloxxado is an opioid antagonist that delivers 8mg of naloxone hydrochloride per spray into the nasal cavity.
Once-Weekly Levomethadone Fast Tracked for Opioid Use Disorder
LYN-014 is an investigational oral, once-weekly, ultra-long-acting, extended-release levomethadone capsule to treat opioid use disorder.
US Drug Overdose Deaths Up ~30% in 2020
Increases seen in overdose deaths from opioids, as well as cocaine and psychostimulants
FDA to Review Buprenorphine Extended-Release Injection for Opioid Use Disorder
Brixadi (buprenorphine) is an investigational, extended-release weekly and monthly subcutaneous injection for moderate to severe opioid use disorder.
MPR Weekly Dose Podcast 82
This week the FDA approved a regenerative skin tissue therapy and a treatment for advanced mastocytosis, while Novavax’s vaccine for COVID and a novel treatment for MDD show promise, also the FDA issue warning concering hand sanitizers.
