Transdermal Cannabidiol Gets Orphan Drug Status for 22q11.2 Deletion Syndrome
The efficacy and safety of Zygel is being evaluated in the INSPIRE study.
Pediatrics
Characteristics ID’d for Under 21s With SARS-CoV-2-Linked Deaths
Teens and young adults, those with underlying medical conditions over-represented among decedents.
Office Dismissal Policy for Families Refusing Vaccines Common
Office policies for dismissal of families more common than physician’s dismissal behavior.
Modafinil in Early Pregnancy Not Tied to Congenital Malformations
Large birth registry study conducted in Norway and Sweden did not show link to major malformations
AAP: Choosing Wisely Recs on Pediatric Pulmonology, Sleep Medicine
The list, titled “Five Things Physicians and Patients Should Question,” was developed by members of the AAP Section on Pediatric Pulmonology and Sleep Medicine.
More Than 20 Percent of Children With COVID-19 Are Asymptomatic
SARS-CoV-2 viral RNA detected for a mean of 14.1 days among children who are asymptomatic.
Evolocumab Cuts LDL-C in Pediatric HeFH Patients
The multicenter, double-blind, placebo-controlled HAUSER-RCT study assessed the efficacy and safety of evolocumab in 157 patients aged 10 to 17 years with HeFH.
Escitalopram Reduces Symptoms of Anxiety in Teens With GAD
Increasing CYP2C19 metabolism linked to reductions in escitalopram Cmax, AUC.
Casimersen Gets Priority Review for Duchenne Muscular Dystrophy
Casimersen is a phosphorodiamidate morpholino oligomer that works by binding to exon 45 of dystrophin pre-mRNA.
Vosoritide NDA for Achondroplasia Submitted for Review
Vosoritide is an investigational analogue of C-type natriuretic peptide.
