Downward Trend for Buprenorphine Misuse From 2015 to 2019
0.7 million of 2.4 million U.S. adults misused buprenorphine in 2019; motivations for misuse include being hooked, physical pain relief
Opioids
Traumatic Brain Injury Tied to Later Opioid Use, Misuse
History of TBI tied to 52 percent increased odds of prescription opioid use, 65 percent increased odds of prescription opioid misuse
MPR Weekly Dose Podcast Episode 93
The FDA weigh up mandatory education for opioid prescribers; There’s an increase in the sale of strong psychoactive THC products; Brukinsa and Exkivity gain approval, respectively; And a number of supplement companies received FDA warning letters.
Opioid Tapering Tied to Higher Risk for Overdose, Mental Health Crisis
Rates of overdose, mental health crises increased after dose tapering among patients prescribed stable, long-term, higher-dose opioid therapy
Significant Percentage of US Adults With Chronic Pain Use Rx Opioids
Prescription opioid use highest for those aged 45 to 64 years; more likely among women, unemployed adults
Once-Weekly Levomethadone Fast Tracked for Opioid Use Disorder
LYN-014 is an investigational oral, once-weekly, ultra-long-acting, extended-release levomethadone capsule to treat opioid use disorder.
The Effect of Opioid Dose and Route on Risk for Respiratory Depression
The researchers’ goals were to evaluate the geographic differences of opioid administration and to examine how opioid administration was associated with respiratory depression.
Should Relaxed Methadone Rules Continue After the Pandemic Ends?
The authors propose evaluating which aspects of previous policy and practices for OUD should resume and which aspects of current policy and practice exemptions should continue.
Opioid Analgesic Approvals Based on Limited Data, Study Says
Opioid products approved by the FDA between 1997 and 2018 relied on short- or intermediate-term studies that did not adequately analyze safety outcomes.
Prenatal Exposure to OMT Does Not Worsen Neonatal Outcomes
Growth parameters similar to those for newborns of women with opioid use disorders during pregnancy
