Tebentafusp Gets Priority Review for Metastatic Uveal Melanoma
The application is supported by data from the phase 2 IMCgp100-202 trial that assessed tebentafusp in 378 HLA-A*02:01-positive adults with previously untreated metastatic uveal melanoma.
Ophthalmic Disorders
NSAID Eye Drops May Suffice for Cataract Surgery Prophylaxis
Initiation of prophylactic treatment 3 days before surgery is not superior to initiation on day of surgery
FDA Approves Generic Version of Durezol
Difluprednate Ophthalmic Emulsion 0.05% is an AB-rated generic equivalent of Durezol.
Intravitreal Methotrexate Gets Orphan Drug Status for Retinitis Pigmentosa
The FDA has granted Orphan Drug designation to ADX-2191 (methotrexate for intravitreal injection) for the treatment of retinitis pigmentosa.
Faricimab Gets Priority Review for Wet AMD, Diabetic Macular Edema
The BLA submission is based on positive results across four phase 3 studies in wet AMD and DME.
Atropine Plus Patching Ups Visual Acuity in Amblyopic Eye
Visual acuity of the affected eye improved more with atropine plus patching than patching alone in children with severe amblyopia
Investigational Vitamin A Therapy Gets Breakthrough Tx Status for Stargardt Disease
ALK-001 is an oral, once daily, chemically-modified form of vitamin A.
Current Use of Hormonal Contraceptives May Up Glaucoma Risk
Authors say risk for glaucoma is low and should not discourage use of hormonal contraceptives
Verkazia Approved for Vernal Keratoconjunctivitis
The approval was based on data from two randomized, multicenter, double-masked, vehicle-controlled trials that evaluated the efficacy and safety of Verkazia in patients with VKC.
Genetic Predisposition + High Caffeine Intake Ups Risk of Increased Intraocular Pressure
High caffeine intake not associated with increased risk for higher IOP or glaucoma, overall; among those with genetic risk, caffeine consumption increases risk of glaucoma
