Add-On Ibrutinib Slows Mantle-Cell Lymphoma in Older Adults
Addition of ibrutinib to chemoimmunotherapy prolongs progression-free survival in older patients with untreated mantle-cell lymphoma
Addition of ibrutinib to chemoimmunotherapy prolongs progression-free survival in older patients with untreated mantle-cell lymphoma
No differences in EFS or OS seen with/without bortezomib overall or in patients with T-cell acute lymphoblastic leukemia
Parsaclisib is an investigational, highly selective, oral inhibitor of phosphatidylinositol 3-kinase delta.
The application is supported by data from several phase 2 studies.
Researchers sought to determine whether C-CAR039 would be safe and effective in patients with relapsed or refractory B-cell non-Hodgkin lymphoma.
Significant reduction found in risk for disease progression/death for C+R versus placebo and rituximab