Enrollment in Fibromyalgia Treatment Study Ends After Disappointing Results
The phase 3 RALLY study is evaluating the efficacy and safety of TNX-102 SL in 514 adult patients with fibromyalgia.
Neuropathic Pain
FDA Approves Spinal Cord Stimulation Therapy for Painful Diabetic Neuropathy
Nevro’s SCS system for painful diabetic neuropathy will be available under the brand name HFX™ for PDN.
Capsaicin 8% Safe and Effective for Diabetic Peripheral Nerve Pain Therapy
Investigators assessed the efficacy and tolerability of a high-concentration capsaicin 8% patch to treat diabetic peripheral nerve pain, either alone or in combination with standard oral therapies.
Qutenza Approved for Painful Diabetic Peripheral Neuropathy of the Feet
The FDA has approved Qutenza® (capsaicin 8% patch; Averitas Pharma) for the treatment of neuropathic pain associated with diabetic peripheral neuropathy of the feet.
Nonopioid Drug Therapies Evaluated for Chronic Pain
Various electronic databases were accessed to obtain randomized controlled trials (RCTs) evaluating nonopioid agents in chronic pain patients. The review focused on 7 chronic pain conditions, including neuropathic pain, fibromyalgia, osteoarthritis, inflammatory arthritis, low back pain, chronic headache, and sickle cell disease.
Lowering Cholesterol Levels May Worsen Nerve Damage in T2DM
Higher number of nerve lesions, declining nerve conduction velocities and amplitudes seen
Decreased Response to Botulinum Toxin Type A Agents Observed Over Time
Preliminary findings showed the decrease in botulinum toxin type A therapeutic effect over time warrants further study.
Is Pregabalin Effective for Chronic, Post-Traumatic Neuropathic Pain?
The primary outcome measure was pain rated in a diary completed by telephone each evening; secondary outcomes included measures of overall status, pain-related activity limitation, and sleep.
Risk of Altered Mental Status in Gabapentin-Treated Patients Explored
The study included 110,184 adults (mean age: 76 years) newly started on gabapentin therapy in Ontario, Canada.
Patients With Trigeminal Neuralgia Receive a Variety of Treatments
A total of 3,685 trigeminal neuralgia patients were included for analysis.
