Musculoskeletal Disorders

FDA Video: Update on Femur Fracture Risk with Bisphosphonates

The FDA has issued updated information on atypical fractures of the femur associated with the use of bisphosphonates to treat osteoporosis. These drugs include Fosamax (alendronate sodium), Actonel (risedronate sodium), Boniva (ibandronate sodium), Atelvia (risedronate sodium), Reclast (zoledronic acid), and their generic equivalents.

Phase 3 study of Exparel for postoperative analgesia

Pacira Pharmaceuticals announced new data from its Phase 3 study to evaluate the efficacy and safety of the intraoperative administration of Exparel (bupivacaine extended-release liposome injection) for prolonged postoperative analgesia in subjects undergoing first metatarsal osteotomy (bunionectomy).

ACTEMRA (tocilizumab) Injection by Genentech

Actemra gains indication for inhibition and improvement of RA

Genentech announced that the FDA has approved Actemra (tocilizumab injection) for the inhibition and slowing of structural joint damage, improvement of physical function, and achievement of major clinical response in adult patients with moderately to severely active rheumatoid arthritis (RA), when given in combination with methotrexate (MTX).