Muscle Spasms Archives - MPR

Muscle Spasms

Dysport Indication Expanded to Include Upper Limb Spasticity Treatment in Children

The Food and Drug Administration (FDA) has expanded the indication of Dysport (abobotulinumtoxinA; Ipsen) to include the treatment of upper limb spasticity in patients aged 2 years and older, excluding spasticity caused by cerebral palsy. Previously, Dysport was only approved to treat lower limb spasticity in patients aged 2 years and older.  The approval was…

Myobloc Approved for the Treatment of Chronic Sialorrhea

The Food and Drug Administration (FDA) has approved Myobloc (rimabotulinumtoxinB injection; US WorldMeds) for the treatment of chronic sialorrhea in adults. The approval was based on multiple studies, including a double-blind, placebo-controlled trial, followed by an open-label treatment period, in 187 patients with chronic, troublesome sialorrhea for at least 3 months. Patients were randomized to…

Botox Approved to Treat Pediatric Patients With Upper Limb Spasticity

The Food and Drug Administration (FDA) has approved Botox (onabotulinumtoxinA; Allergan) for the treatment of upper limb spasticity in pediatric patients 2-17 years of age. The approval was based on data from two phase 3 trials: a 12-week study that evaluated the efficacy and safety of Botox in 234 pediatric patients with upper limb spasticity…