Barriers to Prevention, Eradication of HIV Remain Despite Numerous Advances
Since the first clinical observation of HIV/AIDS in 1981, some 35.4 million people have died from AIDS-related illnesses.
Since the first clinical observation of HIV/AIDS in 1981, some 35.4 million people have died from AIDS-related illnesses.
Temixys combines lamivudine (3TC) and tenofovir disoproxil fumarate (TDF), which are 2 nucleoside reverse transcriptase inhibitors.
Screening recommended for those ages 15 to 65 years, including pregnant women
The researchers found that based on 1 review, HIV transmission risk for condom use without antiretroviral therapy was estimated at 1.14 transmissions/100 person-years (95% confidence interval, 0.56 to 2.04).
The “8.1 Pregnancy” and “12.3 Pharmacokinetics” sections have been updated with data showing no increase in the risk of overall major birth defects with 1st trimester exposure for rilpivirine.
Pre-exposure prophylaxis implementation linked to rapid decline in HIV diagnoses among MSM
“Barriers to the provision of PrEP for persons in populations with the highest rates of annual HIV diagnoses, such as black and Hispanic men and women, need to be better understood to help guide the development of interventions to increase access to and utilization of PrEP,” write the authors.
Delstrigo is approved as a complete regimen whereas Pifeltro is to be administered in combination with other antiretrovirals.
If Tybost is given with atazanavir or darunavir, coadministration with rivaroxaban is not recommended due to a potentially increased bleeding risk.
The researchers found that patients who were receiving a PI had higher rates of hyperlipidemia, diabetes mellitus, and coronary artery disease.