Link Between Serotonin and Depression Questioned
Hypothesis that depression is caused by low serotonin not supported; some evidence shows decrease in serotonin with antidepressant use
Hypothesis that depression is caused by low serotonin not supported; some evidence shows decrease in serotonin with antidepressant use
The designation is supported by data from a phase 2 study, which showed that REL-1017 produced rapid, robust, and sustained antidepressant effects vs placebo.
The expanded approval was based on safety data from an open-label study in 20 patients aged 15 to 17 years with postpartum depression.
Zuranolone is an investigational oral neuroactive steroid GABA-A receptor positive allosteric modulator.
Caplyta is indicated for the treatment of schizophrenia and depressive episodes associated with bipolar I or II disorders, as monotherapy and as adjunctive therapy with lithium or valproate.
The approval was based on data from the phase 3 SERENITY I and II studies that evaluated Igalmi for the acute treatment of agitation associated with schizophrenia and bipolar disorders I and II, respectively.
The use of compounded ketamine nasal spray for home use may place the patient at risk for serious psychiatric adverse events, misuse, and abuse.
Two years after her husband was killed, Mr Z’s grandmother sued several of the hospital’s physicians.
The approval was supported by data from two phase 3 studies that evaluated Caplyta as monotherapy and adjunctive therapy with lithium or valproate in adults with bipolar depression.
The Company will evaluate BNC210 in patients with SAD in the phase 2 PREVAIL trial.