CDC Updates List of Who Is at Highest Risk for COVID-19
Agency now says risk among adults increases steadily with age, and is not limited to those over 65.
Miscellaneous Urogenital Disorders
Allopurinol Does Not Affect eGFR in Chronic Kidney Disease
And, serum urate lowering with allopurinol did not affect GFR in T1DM and diabetic kidney disease.
Co-Dispensing of Benzodiazepines and Opioids Dangerous in HD
Patients on hemodialysis who use opioids concurrently with a short-acting benzodiazepine are especially at risk for early death, a study found.
SARS-CoV-2 Identified in Semen of Men With COVID-19
SARS-CoV-2 present in 26.7% at acute stage of infection, 8.7% of recovering patients.
SGLT2 Inhibitors Linked to Reduced Risk for Serious Renal Events
Data from 3 countries showed drop in serious renal events with sodium-glucose cotransporter 2 inhibitors.
Furosemide Plus Sodium Chloride Not Helpful in Treating SIAD
Adding furosemide with or without sodium chloride to fluid restriction is not more effective than fluid restriction alone at correcting hyponatremia in patients with the syndrome of inappropriate antidiuresis, a study found.
Dapagliflozin CKD Trial Stopped Early Due to “Overwhelming Efficacy”
The decision to stop the trial was made based on positive efficacy data following a recommendation from the study’s independent DMC.
Terlipressin NDA for Hepatorenal Syndrome Type 1 Submitted for Review
Mallinckrodt announced the completion of its rolling submission of a New Drug Application (NDA) to the Food and Drug Administration (FDA) for terlipressin for the treatment of hepatorenal syndrome type 1 (HRS-1).
Anticholinergic Burden Tied to Adverse Effects in Middle Age
Identification of at-risk populations varies by scale used, which could impact clinical practice.
USPSTF Recommends Screening All Adults for Hepatitis C Virus
B recommendation applies to all asymptomatic adults ages 18 to 79 years regardless of risk
