Miscellaneous Hematological Agents Archives - MPR

Miscellaneous Hematological Agents

Methemoglobinemia Following Overuse of OTC Topical Pain Reliever

A report published in the New England Journal of Medicine describes the case of a 25-year-old woman who developed methemoglobinemia following the use of topical benzocaine.  According to clinicians from the Miriam Hospital in Providence, RI, the patient presented with generalized weakness, fatigue, shortness of breath and skin discoloration. “Measurements of arterial blood gases included…

Treatment Granted Orphan Drug Status for Acute Radiation Syndrome

The Food and Drug Administration (FDA) has granted Orphan Drug designation to TP508 (rusalatide acetate; Chrysalis BioTherapeutics) for the treatment of acute radiation syndrome (ARS).  ARS, also known as radiation sickness, is an acute illness caused by irradiation of the body due to high levels of nuclear radiation exposure. The illness affects multiple organ systems…