Pharmacotherapies for Liver Fibrosis, NASH Resolution Ranked
Although NASH is a common cause of chronic liver disease, there is limited evidence surrounding its management.
Miscellaneous Gastrohepatic Disorders
Rifaximin Prevents Overt Hepatic Encephalopathy After TIPS
For patients with cirrhosis, rifaximin reduces odds of overt HE after transjugular intrahepatic portosystemic shunt
Gimoti Nasal Spray Now Available for Diabetic Gastroparesis
Gimoti, a dopamine-2 (D2) antagonist, is a nasal spray formulation of metoclopramide.
Management of Remdesivir-Associated Acute Liver Failure Examined in Case Series
Remdesivir was immediately discontinued in both patients and a continuous infusion of acetylcysteine was initiated.
ACS: Antibiotics Noninferior to Appendectomy for Appendicitis
However, complications occurred more often in the antibiotics group than in the appendectomy group.
Dupilumab Gets Breakthrough Therapy Status for Eosinophilic Esophagitis
The designation was based on results from Part A of a double-blind, placebo-controlled, pivotal phase 3 trial.
FDA Fast Tracks SSAO Inhibitor for Nonalcoholic Steatohepatitis
TERN-201 is a highly-selective semicarbazide-sensitive amino oxidase inhibitor.
Clinical Hold Lifted on Seladelpar for Chronic Liver Diseases
The FDA has lifted the clinical hold on 3 Investigational New Drug applications evaluating seladelpar (CymaBay Therapeutics) for the treatment of non-alcoholic steatohepatitis, primary biliary cholangitis and primary sclerosing cholangitis.
FDA Approves Gimoti Nasal Spray for Diabetic Gastroparesis
The FDA has approved Gimoti™ (metoclopramide; Evoke Pharma) nasal spray for the relief of symptoms in adults with acute and recurrent diabetic gastroparesis.
Human Placental Extract Gets Orphan Drug, Rare Pediatric Disease Status for Necrotizing Enterocolitis
Protego-PD is an oral acellular biotherapeutic derived from post-delivery placentas.
