Clinical Challenge: Discoloration of the Toes
A patient presents with discoloration of her toes, can you make the correct diagnosis?
Miscellaneous Dermatological Conditions
Topical Amitriptyline Gets Orphan Drug Designation for Erythromelalgia
The FDA has granted Orphan Drug designation to ATX01 (proprietary topical amitriptyline; AlgoTherapeutix) for the treatment of erythromelalgia.
Clinical Challenge: Dark Lesion on Lower Lip
A 65-year-old man is referred by his dentist for evaluation of a dark spot on the inside of his lower lip. He reports that the spot has been present for at least 1 year.
Serlopitant Not Statistically Significantly Better Than Placebo in Prurigo Nodularis Studies
Menlo Therapeutics announced topline results from two phase 3 studies of serlopitant for the treatment of pruritus associated with prurigo nodularis.
Clinical Challenge: Itchy Rash on Outer Arm
A 42-year-old woman presents for evaluation of an itchy rash that affects her outer arms and buttocks. The condition was first diagnosed while she was living in the Dominican Republic approximately 4 years ago. At that time, she was treated with dietary modification (gluten-free diet) and oral medication, which resulted in resolution of her symptoms.…
Clinical Challenge: Large Hyperpigmented Patch With Hypertrichosis
A 20-year-old man presents with a large hyperpigmented patch with increased hair growth on his left upper chest and proximal shoulder girdle. Can you make the correct diagnosis?
Wound Care Product Uses Patient’s Own Blood to Promote Healing
RedDress announced the launch of ActiGraft as the first wound care treatment that enables healthcare providers to produce – in real time – a patient’s blood into an autologous whole blood clot tissue to heal wounds and ulcers.
Cool Water for 20 Minutes After Pediatric Burn Improves Outcomes
Adequate cool water reduces the odds of needing a skin graft and hospital admission.
Clinical Challenge: Plaque on the Belly Button
A 3-month-old Hispanic baby is brought to the office for evaluation of a persistent “sore” on her belly button. The sore emerged shortly after the umbilical stump fell off, and occasionally drains a clear fluid. Examination reveals a firm, erythematous, well-circumscribed plaque. Prior evaluation by a pediatrician detected no systemic abnormality.
Skin Hyperpigmentation Linked to Chemotherapy Drug
A recent report published in the New England Journal of Medicine describes the case of a 57-year-old male patient who developed skin hyperpigmentation following chemotherapy that included fluorouracil.
