Monthly Galcanezumab Beneficial for Episodic Migraine Prevention
The researchers found that, compared to placebo, galcanezumab (120mg) significantly reduced migraine headache days (99.6% posterior probability, −4.8 days).
The researchers found that, compared to placebo, galcanezumab (120mg) significantly reduced migraine headache days (99.6% posterior probability, −4.8 days).
Zecuity, launched in September 2015, is a transdermal system that delivers a therapeutic dose via a single-use, battery-powered patch wrapped around the upper arm or thigh.
The studies looked at the safety, tolerability, and efficacy of 4 dose regimens of subcutaneous fremanezumab vs. placebo over 16 weeks.
The non-invasive SpringTMS device is placed at the back of the patient’s head where a forced magnetic pulse is delivered to treat an acute attack or to prevent a future migraine onset.
The use of complementary and alternative medicine (CAM) specifically for the treatment of migraine and headache is “relatively low” in the U.S.
Its agonist effects at the 5-HT1B/1D receptors on intracranial blood vessels and sensory nerves of the trigeminal system result in cranial vessel constriction and inhibition of pro-inflammatory neuropeptide release.
Since September 2015, there have been numerous reports of burns or scars where the patch was applied.
This patient information fact sheet provides information on the definition, symptoms, causes, treatments and self-help measures for migraines.