Lupus Nephritis Drug Voclosporin Shows Efficacy, Safety Over 3 Years
One study focused on patients with severe lupus nephritis, who are at greatest risk for kidney failure.
Medications
Kidney Function Declines More Slowly With SGLT2 Inhibitor
Treatment with an SGLT2 inhibitor may help patients with CKD or type 2 diabetes better preserve their kidney function.
Intravenous vs Oral Iron Does Not Increase CKD Risk
Investigators compared the therapies in a large national cohort of patients with normal kidney function.
Empagliflozin May Reduce Stone Risk
Data from real-world practice and a meta-analysis of randomized controlled trials concur.
Methotrexate Added to Pegloticase for Gout Safe for Kidneys
Investigators report findings from the MIRROR RCT trial, which compared pegloticase plus methotrexate vs placebo for uncontrolled gout.
AKI, CKD Progression Less Likely With Direct Oral Anticoagulants
Danish investigators compared direct oral anticoagulants with vitamin K antagonists in 33,670 patients with atrial fibrillation.
Sotrovimab Is Safe for COVID-19 in Kidney Transplant Recipients
Early administration of sotrovimab may achieve more rapid decline in viral load, according to investigators.
AKI During Immune Checkpoint Inhibitor Therapy May Up Death Risk
Clear management guidelines are needed for AKI during immune checkpoint inhibitor therapy, according to investigators.
Greater PSA Decline Predicts Better 177Lu-PSMA-617 Outcomes in mCRPC
Latest findings are from a post hoc analysis of the phase 3 VISION trial.
Remdesivir Safe Despite Advanced CKD, Study Finds
Remdesivir is not currently recommended for use in patients with an estimated glomerular filtration rate (eGFR) less than 30 mL/min/1.73 m2.
