Belimumab Shows Longer-Term Safety, Efficacy in Lupus Nephritis
The proportion of patients with lupus nephritis achieving renal response with belimumab increased during a 6-month extension study.
Lupus
Voclosporin’s Efficacy Confirmed for All Lupus Nephritis Biopsy Classes
Add-on voclosporin improved complete renal response across all lupus nephritis biopsy classes, with the greatest benefit observed in pure class 3.
MPR Weekly Dose Podcast Episode 66
On this week’s pod: The Moderna vaccine and what we know about its effectiveness against emerging variants; Merck ends it’s development of two vaccines; Two separate treatment combos show promise in reducing hospitalizations and preventing COVID-19, respectively; And the FDA approve a new treatment for lupus nephritis.
Lupkynis Approved for Active Lupus Nephritis
The approval was based on data from the pivotal phase 3 AURORA and phase 2 AURA-LV studies.
MPR Weekly Dose Podcast Episode 44
This week: The government makes a $1.95 billion deal for a COVID-19 vaccine; Promising data from the Oxford vaccine trial; The CDC retakes control of COVID-19 data; Novel calcineurin inhibitor for lupus nephritis gets priority review; And there’s new treatment for narcolepsy.
Drug Shortages Reported as New Program Created to Expedite Treatments for COVID-19
To expedite development, the FDA has created a special emergency program called the Coronavirus Treatment Acceleration Program.
Doctors, Hospitals, Pharmacies Warned Not to Stockpile Meds
Professional societies issue stern warning not to inappropriately prescribe meds for COVID-19.
Glucocorticoid Use Associated With Increased Risk for Cardiovascular Disease in SLE
Researchers addressed the association between cardiovascular risk and glucocorticoids in patients with systemic lupus erythematosus.
Diagnoses of RA, SLE Linked to Increased Opioid Overdose Hospitalization Risk
Researchers compared the rate of opioid overdose-related hospitalizations among patients with systemic lupus erythematosus and rheumatoid arthritis vs the general population.
High Doses of Hydroxychloroquine May Protect Against Thrombosis in SLE
Researchers examined the association of blood levels of hydroxychloroquine with thrombotic events in a longitudinal systemic lupus erythematous cohort.
