Efficacy/Safety of Lefamulin in Severe Community-Acquired Bacterial Pneumonia
Pooled data from the LEAP 1 and 2 trials were used to study the efficacy and safety of lefamulin in patients with CABP at risk for severe pneumonia.
Lung Infections
Use of Bronchodilators Down for Bronchiolitis Treatment in Infants
High hospital-level bronchodilator use not associated with better outcomes; adjustment follows AAP recommendations to limit routine use for bronchiolitis
Asthma, COPD Do Not Increase Mortality Risk in Patients With COVID-19
Asthma and chronic obstructive pulmonary disease (COPD) do not appear to increase the risk of mortality in patients with COVID-19.
Vasoactive Intestinal Peptide Promising Treatment for COVID-19 Respiratory Failure
Use of vasoactive intestinal peptide to treat critical COVID-19 respiratory failure in patients with comorbidities has shown promise.
Expired or Previously Used N95 Respirator Masks: Fitted Filtration Efficiencies Evaluated
Expired or previously used and sterilized N95 respirators can be used when new N95 respirators are unavailable during the COVID-19 pandemic.
Lopinavir-Ritonavir Does Not Offer Substantial Benefit in Severe COVID-19
In patients who were hospitalized with severe coronavirus disease, treatment with lopinavir-ritonavir did not provide a substantial benefit beyond standard care.
Effect of RSV Infection on Lung Function in Transplant Patients
Patients with established chronic lung allograft dysfunction may have a higher risk for respiratory syncytial virus infections, but lung function decline does not appear to be significantly affected.
