COVID-19 mRNA Vaccine Efficacy Wanes Over Time in RCC Cases
Strategies, such as booster doses, appear warranted in this population.
Strategies, such as booster doses, appear warranted in this population.
The decision to discontinue was based on data from pre-planned analyses of the phase 3 PIVOT-09 study and the phase 2 PIVOT-10 study.
In a phase 1 trial, investigators tested whether an oral supplement containing a strain of Clostridium butyricum increases the abundance of certain gut bacteria known to be associated with a better response to immune checkpoint inhibitors.
Treatment-related adverse events of any grade develop in the majority of patients who receive urologic cancer therapies based on immune checkpoint inhibitors, according to a study.
Progression-free, overall survival significantly longer with combo versus sunitinib for advanced renal cell carcinoma
Progression-free survival longer and response rate greater for cabozantinib versus sunitinib in phase 2 trial in adults with PRCC
Prompt diagnosis of AKI and the ability to rule out immune checkpoint inhibitors as the cause may allow patients to continue with cancer immunotherapy.
The approval was based on data from the randomized, open-label phase 3 CheckMate-9ER.