FDA Revises Evusheld EUA Halting Use of the COVID-19 Therapy for Now
Recent data show that the product is unlikely to be active against currently circulating SARS-CoV-2 variants.
Diagnosis & Disease Information
FDA Panel Votes on Rezafungin for Treatment of Candidemia, Invasive Candidiasis
Rezafungin is an investigational echinocandin antifungal that is administered once weekly.
Uptake Low for COVID-19 Vaccine Boosters in Immunocompromised Adults
Authors found low adherence to CDC recommendations for boosters, with older adults more likely to receive at least four mRNA COVID-19 vaccine doses
Seniors Had High Burden of RSV-Positive Respiratory Infection Before COVID-19
Following sharp decline during COVID-19, RSV-positive acute respiratory infection reemerged during summer 2021, and is linked to lower QOL
Algorithm Predicts Urinary Tract Infection Without Microscopy
Authors say the new algorithm could be used to safely withhold antibiotics in low-risk patients in the primary care setting
Two Cases of New Drug-Resistant Gonorrhea Strain Reported in Massachusetts
The two cases do not appear to have a direct connection to each other
MPR Weekly Dose Podcast #145
Pfizer-BioNTech bivalent vaccine under investigation; Trial evaluating HIV prevention vaccine discontinued; Early detection sepsis test cleared; Trial results for RSV-associated disease vaccine; Combo Tx for HCC recurrence shows promise.
Respiratory Virus Coinfection May Up SARS-CoV-2 Severity in Children Under 5
For children younger than 5 years, having any viral codetection or rhinovirus/enterovirus codetection significantly linked to severe illness
FDA Clears Test to Aid in Early Detection of Sepsis
The semi-quantitative test uses a whole blood sample to assess cellular host response by analyzing the biophysical properties of white blood cells.
Lack of Efficacy Ends Trial Evaluating Janssen’s HIV Vaccine Candidate
The decision to discontinue the study was made based on an analysis from an independent data and safety monitoring board.
