Influenza surveillance and response remains an ongoing, and changing, challenge-and pandemic preparedness goes well beyond stockpiling vaccines, noted speakers at IDWeek 2015’s closing plenary session.
Long-term testosterone replacement therapy (TRT) is associated with an increased risk of cardiovascular events (CVE) and death among HIV-positive men, authors of a retrospective chart review reported at IDWeek 2015.
For treatment of uncomplicated, outpatient urinary tract infection (UTI), fewer failures were seen with empiric cephalexin than with trimethoprim/sulfamethoxazole (TMP-SMX) or amoxicillin, researchers presented at IDWeek 2015.
Children with uncomplicated cellulitis may be safely treated at home, as they are unlikely to have bacteremia, Laila F. Ibrahim, MBBChBAO, from the Royal Children’s Hospital @ Home Department in Parkville, Australia, reported at IDWeek 2015.
Among HIV-positive patients, hepatitis C virus (HCV) coinfection, low baseline CD4 counts and other factors increase the risk of tenofovir-associated renal failure, reported authors of a retrospective cohort study presented at IDWeek 2015.
There was no statistically significant difference in clinical outcomes between patients with methicillin-resistant Staphylococcus aureus (MRSA) pneumonia who were treated with linezolid and those treated with vancomycin except mortality, reported ManShan Celica Tong, PharmD, MPH, from Medical University of South Carolina, Charleston, SC, at IDWeek 2015.
The combination of ceftolozane and tazobactam showed comparable outcomes to levofloxacin in the treatment of complicated pyelonephritis, according to results from the Phase 3 ASEPCT-cUTI trial presented at IDWeek 2015.
Tigecycline used as adjunctive therapy for severe Clostridium difficile-associated diarrhea (CDAD) led to higher rates of colectomy and higher mortality, according to results of a multicenter study presented by Candace Marr, DO, from the Catholic Health System and The State University of New York at Buffalo, Buffalo, NY, at IDWeek 2015.
Neonatal acellular pertussis vaccination may be a safe alternative to maternal immunization, according to efficacy data presented at IDWeek 2015.
Patients with HIV and tuberculosis (TB) coinfection are discontinuing first-line antitubercular therapy (ATT) at disturbingly high rates because of side effects like skin reactions, gastrointestinal symptoms, and hepatotoxicity, according to study findings reported at IDWeek 2015.
