Ready-to-Use Norepinephrine Formulation Now Available
Norepinephrine is a catecholamine indicated for restoration of blood pressure in adult patients with acute hypotensive states.
Hypotension
Study Evaluating Ampreloxetine for Neurogenic Orthostatic Hypotension Misses Endpoint
The phase 3 study was evaluating the efficacy and safety of ampreloxetine for the treatment of symptomatic neurogenic orthostatic hypotension in patients 30 years of age and older.
Rezipres Approved for Intraoperative Hypotension
The FDA has approved Rezipres (ephedrine hydrochloride) for the treatment of clinically important hypotension occurring in the setting of anesthesia.
Gender-Affirming Hormone Therapy Tied to Systolic BP Changes
Within two to four months, increases, decreases in systolic BP seen in transmasculine, transfeminine adults, respectively
Possible Sterility Breach Prompts Recall of Phenylephrine Hydrochloride Injection
A non-integral crimped vial overseal may result in a non-sterile product.
Emerphed Now Available for Intraoperative Hypotension
Nexus Pharmaceuticals announced the launch of Emerphed™, a premixed, ready-to-use formulation of ephedrine.
Ready-to-Use Ephedrine Injection Gets FDA Approval
The FDA approved the New Drug Application (NDA) for Emerphed (Nexus Pharmaceuticals), a premixed, ready-to-use formulation of ephedrine sulfate.
Antiarrhythmic Agent Linked to Patient’s Blue-Gray Skin Discoloration
A recent report published in the New England Journal of Medicine describes the case of a patient with persistent skin discoloration associated with the use of the antiarrhythmic agent amiodarone. The 81-year-old man presented to the emergency department after a fall, which was eventually attributed to orthostatic hypotension. His medical history included atrial fibrillation and…
Neurogenic Orthostatic Hypotension: Treatments
Treatment of Neurogenic Orthostatic Hypotension
MPR Weekly Dose Podcast: Episode 15
Back from our Thanksgiving break, this week we talk about the new approval for sickle cell disease; the re-introduction of a product that was taken off the market in the 60’s; The first ready-to-use phenylephrine injection; A new ultrasound enhancing agent; And an approval for arthritis.
