Possible Sterility Breach Prompts Recall of Phenylephrine Hydrochloride Injection
A non-integral crimped vial overseal may result in a non-sterile product.
Hypotension
Emerphed Now Available for Intraoperative Hypotension
Nexus Pharmaceuticals announced the launch of Emerphed™, a premixed, ready-to-use formulation of ephedrine.
Ready-to-Use Ephedrine Injection Gets FDA Approval
The FDA approved the New Drug Application (NDA) for Emerphed (Nexus Pharmaceuticals), a premixed, ready-to-use formulation of ephedrine sulfate.
Antiarrhythmic Agent Linked to Patient’s Blue-Gray Skin Discoloration
A recent report published in the New England Journal of Medicine describes the case of a patient with persistent skin discoloration associated with the use of the antiarrhythmic agent amiodarone. The 81-year-old man presented to the emergency department after a fall, which was eventually attributed to orthostatic hypotension. His medical history included atrial fibrillation and…
Neurogenic Orthostatic Hypotension: Treatments
Treatment of Neurogenic Orthostatic Hypotension
MPR Weekly Dose Podcast: Episode 15
Back from our Thanksgiving break, this week we talk about the new approval for sickle cell disease; the re-introduction of a product that was taken off the market in the 60’s; The first ready-to-use phenylephrine injection; A new ultrasound enhancing agent; And an approval for arthritis.
Biorphen, a Ready-to-Use Phenylephrine Formulation, Now Available
Eton Pharmaceuticals announced the availability of Biorphen (phenylephrine HCl) injection as the first ready-to-use injectable formulation of phenylephrine. Biorphen, an α-1 adrenergic receptor agonist, is indicated for the treatment of clinically important hypotension resulting primarily from vasodilation in the setting of anesthesia. It is supplied as a 0.1mg/mL solution in 5mL single-dose ampules; this corresponds…
Ready-to-Use Injectable Formulation of Phenylephrine Approved
Following the development of hypotension during anesthesia, the administration of phenylephrine has been shown to raise systolic and mean blood pressure.
FDA: Cybersecurity Vulnerabilities Identified With Certain Medical Devices, Hospital Networks
The Food and Drug Administration (FDA) has issued an alert regarding a set of cybersecurity vulnerabilities that may potentially introduce risks for certain medical devices and hospital networks. Security researchers have determined 11 vulnerabilities, referred to as “URGENT/11”, that may potentially allow an unauthorized user to take control of a facilities’ medical network leading to…
FDA Warns of “Cure-All” Products That Actually Contain Bleach
The FDA is warning consumers to stop using products known as Miracle or Master Mineral Solution, Miracle Mineral Supplement, MMS, Chlorine Dioxide Protocol, and Water Purification Solution due to numerous reports of significant health issues.
