New Drug Product: Jatenzo
This slideshow shows drug information for Jatenzo. Click here for the complete Jatenzo monograph.
Hypogonadism
MPR Weekly Dose Podcast Episode 21
This week on the Pod we cover an insulin pump recall; Pharmacies running out of supplies in light of Covid-19 fears; Investigational Alzheimer disease treatments not meeting trial end points; A new cardiac ultrasound device; and a new oral testosterone replacement therapy.
Jatenzo, an Oral Testosterone Replacement Therapy, Now Available
Jatenzo® (testosterone undecanoate; Clarus Therapeutics), an oral testosterone replacement therapy, is now available for the treatment of hypogonadism.
Folic Acid, Zinc Supplements in Men No Benefit in Infertility
No significant improvement seen in semen quality, live births among couples seeking infertility treatment
Guideline Issued for Testosterone Therapy in Adult Men
Testosterone recommended for men with sexual dysfunction who want to improve sexual function.
Testosterone Therapy Tied to Increase in Short-Term VTE Risk
Among men with and without hypogonadism, testosterone therapy linked to elevated VTE risk
FDA Again Rejects NDA for Oral Testosterone Product Candidate
The Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) to Lipocine regarding the New Drug Application for Tlando (testosterone undecanoate), an oral testosterone product candidate for testosterone replacement therapy in adult males with primary hypogonadism or hypogonadotropic hypogonadism. In the CRL, the Agency noted that the trial establishing the efficacy of…
Selective Estrogen Receptor Modulators May Be Effective for Male Infertility
Selective estrogen receptor modulators (SERMs) may be effective for treating male infertility, according to a recent systematic review and meta-analysis published in Expert Opinion on Pharmacotherapy. SERMs are compounds that exhibit tissue-selective estrogen receptor agonist and antagonist activity. Clomiphene citrate and tamoxifen are two agents commonly used for the off-label management of male infertility. To…
New Oral Tx Approved for Males With Certain Types of Hypogonadism
The Food and Drug Administration (FDA) has approved Jatenzo (testosterone undecanoate; Clarus Therapeutics) capsules for testosterone replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone: congenital or acquired primary hypogonadism or hypogonadotropic hypogonadism.
Xyosted Now Available for Treatment of Testosterone Deficiency
Prior to starting Xyosted, the patient’s baseline cardiovascular risk should be considered and blood pressure should be adequately controlled.
