Statin Use May Be Safely Continued During Pregnancy
Higher risk seen for low birth weight and preterm birth with statins, but no tie to congenital anomalies
Hyperlipoproteinemias
New Drugs Approved in 2021
Visit our New Drug Products page to stay up-to-date on the latest drug approvals.
December 2021: 5 Notable Drug Approvals
Review the December 2021 notable drug approvals.
Leqvio Approved as Twice-Yearly Injection to Lower LDL-C in High-Risk Patients
The approval was based on data from the ORION-9, ORION-10, and ORION-11 trials that evaluated Leqvio in patients 18 years of age and older with HeFH or clinical ASCVD.
LDL-C Reduction Observed With Inclisiran Regardless of BMI
Inclisiran is a chemically synthesized small interfering RNA that targets proprotein convertase subtilisin-kexin type 9 (PCSK9) messenger RNA.
Statins May Be Tied to Lower Risk for COVID-19 Death
Statin treatment tied to moderately lower COVID-19 mortality in large population study accounting for preexisting health conditions and other factors
Repatha Approved for Younger Patients with HeFH and HoFH
The approval of Repatha was also expanded to include patients 10 years of age and older with HoFH.
Guidance Issued for Reducing ASCVD Risk in Hypertriglyceridemia
Factors to consider include evaluation of secondary causes, optimization of diet and lifestyle interventions, implementation of statin therapy
MPR Weekly Dose Podcast Episode 87
This week we have news of the FDA requesting a change to statin prescribing labels, a new vaccine for streptococcus pneumoniae, a new plaque psoriasis cream, a stem cell therapy gets fast tracked as a possible Parkinson disease treatment, and there’s a new treatment approved for Progressive Familial Intrahepatic Cholestasis.
FDA Requests Removal of Pregnancy Contraindication for Statins
The FDA conducted a comprehensive review of all available data associated with the use of statins during pregnancy.
