While DAAs have improved the treatment of chronic HCV infection by eliciting higher rates of sustained virologic response, they also interact with a number of agents that could potentially limit their effectiveness.
Baseline testing for HCP should be conducted as soon as possible after exposure, ideally within 48 hours
The VOYAGE-1 and VOYAGE-2 trials included HCV genotype 1, 2, 3, 4, or 6 infected patients with cirrhosis (VOYAGE-1) or compensated cirrhosis (VOYAGE-2) who were treatment-naive or PRS ([peg]interferon, ribavirin and/or sofosbuvir) treatment-experienced.
Epclusa is a fixed-dose combination of sofosbuvir, a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor, and velpatasvir, an HCV NS5A inhibitor.
Risk for 10-year liver-related mortality also lower among aspirin users with chronic hepatitis B or C.
The Food and Drug Administration (FDA) has approved Harvoni (ledipasvir and sofosbuvir; Gilead) and Sovaldi (sofosbuvir; Gilead) for use in younger patients with chronic hepatitis C virus (HCV). Specifically, Harvoni is now indicated for use in patients 3 years of age and older with: HCV genotypes 1, 4, 5, or 6 infection without cirrhosis or…
FDA) is warning healthcare professionals that cases of liver decompensation, including liver failure and death, have been linked to certain hepatitis C drugs administered to patients with moderate to severe hepatic impairment.
The FDA is warning consumers to stop using products known as Miracle or Master Mineral Solution, Miracle Mineral Supplement, MMS, Chlorine Dioxide Protocol, and Water Purification Solution due to numerous reports of significant health issues.
“These results are truly exciting and demonstrate, in a large multicenter controlled trial, the impressive efficacy of Sci-B-Vac at a dose half that of other hepatitis B vaccines,” said one of the lead investigators.
For adults with chronic hepatitis C virus (HCV) infection, direct-acting antivirals are associated with a reduced risk for mortality and hepatocellular carcinoma, according to a study published online February 11 in The Lancet.
