EPO Does Not Improve Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy
Death, neurodevelopmental impairment rates similar for newborns receiving erythropoietin, or placebo, combined with therapeutic hypothermia
Diagnosis & Disease Information
Lusutrombopag Under Priority Review for Thrombocytopenia in Liver Disease
The primary endpoint was the number of patients who required no platelet transfusion priory to primary invasive procedure and no rescue therapy for bleeding for 7 days post-procedure.
APAP, Non-APAP Induced Acute Liver Failure More Likely in Women
Gender differences have been established for most chronic liver diseases but less is known with acute liver failure.
Mortality Rates in Cirrhosis, UGIB Cut With Timely Antibiotic Administration
Timely administration of antibiotics is associated with a reduction in mortality among patients with cirrhosis and upper gastrointestinal bleeding (UGIB), according to a study published in the November issue of Clinical Gastroenterology and Hepatology.
Low Risk of Hepatic Decompensation With PrOD Regimen, Study Finds
The overall risk of hepatic decompensation in patients treated with the paritaprevir/ritonavir, ombitasvir, dasabuvir (PrOD) regimen during and up to 12 weeks after completion of treatment was low, Adeel A. Butt, MD, MS, of the VA Pittsburgh Healthcare System, Pittsburgh, PA, told IDWeek 2016 attendees.
Is There a Benefit to Adding Rifaximin to Lactulose in Acute Hepatic Encephalopathy?
Adding rifaximin to lactulose treatment for acute hepatic encephalopathy did not shorten hospital length of stay but it did lower readmission rates at 180 days, study authors reported in a study published in the Journal of Pharmacy Practice.
Liver Injury from CAM Just as Bad as with Prescription Meds
Complementary and alternative medicine (CAM)-induced drug-induced liver injury (DILI) is as severe in presentation as that seen with prescription medicine (PM)-induced DILI with higher rates of transplantation and lower transplant-free survival in patients who progress to acute liver failure, a new report in The American Journal of Gastroenterology has shown.
Drug Used for Organ Rejection Prophylaxis Effective in Autoimmune Hepatitis
Mycophenolate mofetil appears safe and effective for the treatment of autoimmune hepatitis (AIH), according to the results of a study published in Alimentary Pharmacology & Therapeutics.
Hep E Transmission Occurs After Plasma Exchange
A case of hepatitis E virus (HEV) infection has been reported in a kidney transplant recipient, according to a research letter published online March 1 in the Annals of Internal Medicine.
Modest Survival Benefit With Sorafenib in Advanced HCC Patients
Sorafenib was associated with a modest survival benefit in patients with advanced hepatocellular carcinoma (HCC), particiularly in patients with decompensation, data presented at The Liver Meeting® 2015 presented.
