Optimal Difelikefalin Dose Reported for Pruritus in Hemodialysis
In a previous US phase 2 trial, no clear dose response was observed with difelikefalin.
In a previous US phase 2 trial, no clear dose response was observed with difelikefalin.
The source of the chemicals is from the silicone tubing used as a part of the hydraulics in the machine and the dialysate lines.
Apixaban is a direct oral anticoagulant that relies less on kidney excretion.
A recent findings, if validated, may partly explain inter-individual differences in the response to cinacalcet treatment for secondary hyperparathyroidism.
Until now, no other treatment has been shown to reduce heart attack risk in patients on dialysis.
New data from DOPPS support previous studies finding higher risk for gastrointestinal injury after use of sodium polystyrene sulfonate.
Dissatisfaction with taking phosphate binders may influence medication adherence and ultimately clinical outcomes, according to investigators.
Study is the largest to explore this potential safety issue to date.
Tenapanor inhibits the sodium/hydrogen exchanger 3 to control serum phosphorus in adults with CKD on dialysis.
Unlike phosphate binders, tenapanor decreases paracellular phosphate absorption in the intestine.