Recommendations Developed for Treating Hypercalcemia of Malignancy
Authors strongly recommend treatment with denosumab or an intravenous bisphosphonate for adults with HCM
Diagnosis & Disease Information
Investigational Therapy Gets Fast Track Status for Glioblastoma Multiforme
In preclinical studies, WP1122 has shown to increase cellular uptake of 2-DG, increase drug half-life, and increase the ability to cross the blood brain barrier.
Neoadjuvant Pembrolizumab Not Tied to More AEs in Oral Cavity SCC
No increased perioperative morbidity seen among patients with local regionally advanced oral cavity squamous cell carcinoma
Gabapentin May Cut Opioid Needs for Oral Mucositis Pain During RT
Findings seen in studies involving patients receiving chemoradiotherapy for nonmetastatic squamous cell carcinoma of head and neck
Silmitasertib Granted Orphan Drug Status for Medulloblastoma
Silmitasertib is a first-in-class potent and highly selective inhibitor of casein kinase 2 (CK2).
Tislelizumab Plus Chemotherapy as First-Line Tx Improves PFS for Nasopharyngeal Cancer
The phase 3 RATIONALE 309 trial evaluated the efficacy and safety of tislelizumab plus chemotherapy in 263 adults with recurrent or metastatic nasopharyngeal cancer (RM-NPC).
Toripalimab Gets Priority Review for Nasopharyngeal Carcinoma
The application is supported by data from the phase 2 POLARIS-02 and phase 3 JUPITER-02 studies.
Multimodel Anesthesia May Cut Opioid Usage After Head and Neck Cancer Surgery
Study authors analyzed the safety and efficacy of using MMA for patients undergoing head and neck surgery.
HPV Vaccine Will Have Modest Impact on Oropharynx Cancer Incidence by 2045
However, reductions in oropharynx cancer incidence should be seen among young and middle-aged adults
Carboplatin Intensification Beneficial for Group 3 Medulloblastoma
Therapy intensification with carboplatin improved five-year event-free survival in children with high-risk group 3 medulloblastoma only
