Mouthwashes Show Promise in Reducing Chemo-Related Oral Mucositis Pain
Two separate oral rinses were found to reduce pain from oral mucositis and mouth sores in patients receiving radiation therapy for head and neck cancers when compared to placebo.
Head and Neck Cancer
Neoadjuvant PD-1 Blockade Seems Effective in Glioblastoma
Neoadjuvant administration of programmed cell death protein 1 (PD-1) blockade seems to enhance local and systemic antitumor immune response in glioblastoma, according to a study published online in Nature Medicine.
Pembrolizumab Promising for Metastatic Head, Neck SCC
For patients with recurrent or metastatic head and neck squamous cell carcinoma, pembrolizumab has a favorable safety profile and is associated with prolongation of overall survival.
Paternal Methotrexate Use and Congenital Malformations: Is There Any Link?
Data was pulled from the PubMed, Embase, Cochrane Central, and CINAHL databases to study possible links between men using methotrexate and congenital malformations in offspring.
NIH Releases Large-Scale Dataset of CT Images
Unlike most lesion medical image datasets currently available, which can detect only 1 type of lesion, DeepLesion has much diversity and contains critical radiology findings from across the body, including lung nodules, liver tumors, and enlarged lymph nodes.
ASCO: Undertreatment Seen for Women With Head & Neck Cancer
In generalized competing event analysis, the relative hazard ratio for death from HNC versus other causes was increased for female patients (adjusted relative hazard ratio, 1.92), indicating that female patients may be undertreated.
Proactive Swallowing Rehab Program Helpful in Phalangeal CA
Among patients receiving a swallow evaluation, feeding tube requirements were less frequent for those receiving a pretreatment evaluation compared with referral during or after treatment (31% versus 61 and 64%, respectively).
Opioid Rx Patterns Examined for Head and Neck, Lung and Colon Cancer
The researchers identified 168 prescriptions associated with HNCA and 571 with LCCA diagnoses. Compared to patients with LCCA, patients with HNCA had significantly increased odds of being prescribed an opioid (odds ratio, 1.68).
FDA Approves New Dosing Option for Opdivo
This approval will provide healthcare professionals the flexibility to customize patient care.
Outcomes Assessed for HPV-Related Head, Neck CA Requiring Resections
Surgery and adjuvant therapy used for invasive nodal disease requiring extensive neck dissection. Researchers found that regional recurrences were seen in 6% of patients, and 17% experienced distant recurrences.
