No Increased Cardiovascular Risk With Febuxostat vs Allopurinol
In contrast to CARES, FAST found that treatment with febuxostat was not associated with an increase in cardiovascular or all-cause death compared with allopurinol in patients with gout.
Gout
Updated 2020 American College of Rheumatology Gout Management Guidelines
The American College of Rheumatology developed guidelines for the management of gout, including use of urate-lowering therapy, flare treatment, and lifestyle and medication recommendations.
Liquid Formulation of Colchicine Now Available for Gout Management
Avion Pharmaceuticals announced the launch of Gloperba (colchicine) oral solution for prophylaxis of gout flares in adults. Gloperba is a ready-to-use solution for oral administration containing 0.12mg/mL of colchicine. The approval was based on evidence from published literature supporting the efficacy of colchicine in patients with chronic gout. In 2 randomized clinical trials, treatment with…
Risk of Hypersensitivity Reactions Assessed With Commonly Used Gout Treatments
Allopurinol and febuxostat were found to be associated with a higher risk of hypersensitivity reactions when compared to colchicine, according to the results of a recently published population-based study.
Amlodipine Better BP Drug for Lower Long-Term Risk for Gout
Compared with chlorthalidone and lisinopril, amlodipine associated with lower risk for gout.
Corticosteroids Compared for Pre-Infusion Prophylaxis in Patients Receiving Pegloticase for Gout
Compared with intravenous hydrocortisone, IV methylprednisolone appears to be more beneficial as a pre-infusion prophylaxis therapy in patients receiving pegloticase, according to the findings of a recently published review.
Acute Myocardial Infarction Hospitalizations Occur at Younger Age in Gout, RA vs Osteoarthritis
Researchers assessed the demographics associated with the admission of acute myocardial infarction and evaluated the differences between rheumatoid arthritis and gout and osteoarthritis.
Lower Risk for Gout With SGLT2 Inhibitors vs GLP1 Agonists in Type 2 Diabetes
The following article is a part of conference coverage from the 2019 American College of Rheumatology/Association of Rheumatology Professionals (ACR/ARP) Annual Meeting, being held in Atlanta, Georgia. The team at MPR will be reporting on the latest news and research conducted by leading experts in rheumatology. Check back for more from the 2019 ACR/ARP Annual…
Opioids Commonly Prescribed to Gout Patients Discharged From the ED
Opioids are commonly prescribed for acute gout management following discharge from the emergency department.
Gloperba Approved for the Prophylaxis of Gout Flares
The Food and Drug Administration has approved Gloperba (colchicine; ROMEG Therapeutics) Oral Solution for the prophylaxis of gout flares in adults. It is the first liquid formulation of colchicine to be approved by the FDA for this indication.
