No Difference Between Early and Late Allopurinol Initiation for Acute Gout Flare
Researchers compared the time to complete resolution of acute gout flare between early and late allopurinol initiation.
Gout
Urate-Lowering Therapy Associated With Decreased Gout Flare Risk
Patients with asymptomatic hyperuricemia who achieved serum uric acid levels of 6.0 mg/dL or less while on urate-lowering therapy had fewer gout flare episodes, a study found.
Pegloticase Use for Uncontrolled Gout in the Dialysis Population Described
New study is the first to characterize pegloticase use in the dialysis population.
No Increased Cardiovascular Risk With Febuxostat vs Allopurinol
In contrast to CARES, FAST found that treatment with febuxostat was not associated with an increase in cardiovascular or all-cause death compared with allopurinol in patients with gout.
Updated 2020 American College of Rheumatology Gout Management Guidelines
The American College of Rheumatology developed guidelines for the management of gout, including use of urate-lowering therapy, flare treatment, and lifestyle and medication recommendations.
Liquid Formulation of Colchicine Now Available for Gout Management
Avion Pharmaceuticals announced the launch of Gloperba (colchicine) oral solution for prophylaxis of gout flares in adults. Gloperba is a ready-to-use solution for oral administration containing 0.12mg/mL of colchicine. The approval was based on evidence from published literature supporting the efficacy of colchicine in patients with chronic gout. In 2 randomized clinical trials, treatment with…
Risk of Hypersensitivity Reactions Assessed With Commonly Used Gout Treatments
Allopurinol and febuxostat were found to be associated with a higher risk of hypersensitivity reactions when compared to colchicine, according to the results of a recently published population-based study.
Amlodipine Better BP Drug for Lower Long-Term Risk for Gout
Compared with chlorthalidone and lisinopril, amlodipine associated with lower risk for gout.
Corticosteroids Compared for Pre-Infusion Prophylaxis in Patients Receiving Pegloticase for Gout
Compared with intravenous hydrocortisone, IV methylprednisolone appears to be more beneficial as a pre-infusion prophylaxis therapy in patients receiving pegloticase, according to the findings of a recently published review.
Acute Myocardial Infarction Hospitalizations Occur at Younger Age in Gout, RA vs Osteoarthritis
Researchers assessed the demographics associated with the admission of acute myocardial infarction and evaluated the differences between rheumatoid arthritis and gout and osteoarthritis.
